Randomized controlled trial on the effectiveness of silver diamine fluoride in arresting caries in Lagos, Nigeria

Treatment of dental caries in children still remains challenging due to lack of cooperation with conventional treatment modalities. Recently, the use of Silver Diamine Fluoride (SDF) has proved useful in addressing this challenge. Aim: This clinical trial aimed to evaluate the effectiveness of Silv...

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Autores principales:	Moses Okechukwu Azouru, Modupe Olufunmilayo Ashiwaju, Augustine Edomwonyi, Afolabi Oyapero, Bola Obisesan, Aderinsola Omotuyole
Formato:	article
Lenguaje:	EN
Publicado:	Universidade Estadual de Campinas 2021
Materias:	Dental caries Glass ionomer cement Fluorides, topical Dentistry RK1-715
Acceso en línea:	https://doaj.org/article/7a52715e31554f1789965a5f7e523dbe
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spelling	oai:doaj.org-article:7a52715e31554f1789965a5f7e523dbe2021-11-05T14:02:32ZRandomized controlled trial on the effectiveness of silver diamine fluoride in arresting caries in Lagos, Nigeria 10.20396/bjos.v21i00.86663411677-3225https://doaj.org/article/7a52715e31554f1789965a5f7e523dbe2021-11-01T00:00:00Zhttps://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8666341https://doaj.org/toc/1677-3225 Treatment of dental caries in children still remains challenging due to lack of cooperation with conventional treatment modalities. Recently, the use of Silver Diamine Fluoride (SDF) has proved useful in addressing this challenge. Aim: This clinical trial aimed to evaluate the effectiveness of Silver Diamine Fluoride (SDF) in arresting caries in children in Lagos, Nigeria. Methods: This was a phase III balanced randomized controlled school based interventional study on 240 children. The study group was treated with SDF while GIC was used in the control group. Follow up visits in 2 weeks, 1 month, and 3 months were carried out to assess the treatment outcome. Inferential statistics with the use of Pearson Chi-square test and Independent Student t-test were used at 5% level of significance. Results: There was significant relationship between SDF and caries arrest in 2 weeks, 1 month and 3 months’ assessment period (p = 0.001). The control group showed continuous decline (71.7%, 54.3% and 50.9%) in restorative success from 2 weeks to 3 months respectively. The mean ± SD and Confidence Interval (CI) of arrested caries in the SDF group were 113± 1.24 and 113.1 – 113.5 respectively. In the control group the mean ± SD and CI of restorative success were 69.3±11.8 and 67.2 – 71.4. The effect size was 5.24. Conclusion: The result of the study showed that SDF was effective in arresting caries in children without any harm and there was statistically significant difference in the use of 38% SDF in arresting caries in children. Moses Okechukwu AzouruModupe Olufunmilayo AshiwajuAugustine EdomwonyiAfolabi OyaperoBola ObisesanAderinsola OmotuyoleUniversidade Estadual de CampinasarticleDental cariesGlass ionomer cementFluorides, topicalDentistryRK1-715ENBrazilian Journal of Oral Sciences, Vol 21, Iss 00 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Dental caries Glass ionomer cement Fluorides, topical Dentistry RK1-715
spellingShingle	Dental caries Glass ionomer cement Fluorides, topical Dentistry RK1-715 Moses Okechukwu Azouru Modupe Olufunmilayo Ashiwaju Augustine Edomwonyi Afolabi Oyapero Bola Obisesan Aderinsola Omotuyole Randomized controlled trial on the effectiveness of silver diamine fluoride in arresting caries in Lagos, Nigeria
description	Treatment of dental caries in children still remains challenging due to lack of cooperation with conventional treatment modalities. Recently, the use of Silver Diamine Fluoride (SDF) has proved useful in addressing this challenge. Aim: This clinical trial aimed to evaluate the effectiveness of Silver Diamine Fluoride (SDF) in arresting caries in children in Lagos, Nigeria. Methods: This was a phase III balanced randomized controlled school based interventional study on 240 children. The study group was treated with SDF while GIC was used in the control group. Follow up visits in 2 weeks, 1 month, and 3 months were carried out to assess the treatment outcome. Inferential statistics with the use of Pearson Chi-square test and Independent Student t-test were used at 5% level of significance. Results: There was significant relationship between SDF and caries arrest in 2 weeks, 1 month and 3 months’ assessment period (p = 0.001). The control group showed continuous decline (71.7%, 54.3% and 50.9%) in restorative success from 2 weeks to 3 months respectively. The mean ± SD and Confidence Interval (CI) of arrested caries in the SDF group were 113± 1.24 and 113.1 – 113.5 respectively. In the control group the mean ± SD and CI of restorative success were 69.3±11.8 and 67.2 – 71.4. The effect size was 5.24. Conclusion: The result of the study showed that SDF was effective in arresting caries in children without any harm and there was statistically significant difference in the use of 38% SDF in arresting caries in children.
format	article
author	Moses Okechukwu Azouru Modupe Olufunmilayo Ashiwaju Augustine Edomwonyi Afolabi Oyapero Bola Obisesan Aderinsola Omotuyole
author_facet	Moses Okechukwu Azouru Modupe Olufunmilayo Ashiwaju Augustine Edomwonyi Afolabi Oyapero Bola Obisesan Aderinsola Omotuyole
author_sort	Moses Okechukwu Azouru
title	Randomized controlled trial on the effectiveness of silver diamine fluoride in arresting caries in Lagos, Nigeria
title_short	Randomized controlled trial on the effectiveness of silver diamine fluoride in arresting caries in Lagos, Nigeria
title_full	Randomized controlled trial on the effectiveness of silver diamine fluoride in arresting caries in Lagos, Nigeria
title_fullStr	Randomized controlled trial on the effectiveness of silver diamine fluoride in arresting caries in Lagos, Nigeria
title_full_unstemmed	Randomized controlled trial on the effectiveness of silver diamine fluoride in arresting caries in Lagos, Nigeria
title_sort	randomized controlled trial on the effectiveness of silver diamine fluoride in arresting caries in lagos, nigeria
publisher	Universidade Estadual de Campinas
publishDate	2021
url	https://doaj.org/article/7a52715e31554f1789965a5f7e523dbe
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Randomized controlled trial on the effectiveness of silver diamine fluoride in arresting caries in Lagos, Nigeria

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