Pharmacist involved education program in a multidisciplinary team for oral mucositis: Its impact in head-and-neck cancer patients.

<h4>Objectives</h4>This retrospective study examined how a pharmacist-involved education program in a multidisciplinary team (PEMT) for oral mucositis (OM) affected head-and-neck cancer (HNC) patients receiving concurrent chemoradiotherapy (CCRT).<h4>Materials and methods</h4>...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Kensuke Yoshida, Yasumitsu Kodama, Yusuke Tanaka, Kyongsun Pak, Marie Soga, Akira Toyama, Kouji Katsura, Ritsuo Takagi
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/7a69c21990f8404ba8e9364f4896cc74
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:7a69c21990f8404ba8e9364f4896cc74
record_format	dspace
spelling	oai:doaj.org-article:7a69c21990f8404ba8e9364f4896cc742021-12-02T20:16:19ZPharmacist involved education program in a multidisciplinary team for oral mucositis: Its impact in head-and-neck cancer patients.1932-620310.1371/journal.pone.0260026https://doaj.org/article/7a69c21990f8404ba8e9364f4896cc742021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0260026https://doaj.org/toc/1932-6203<h4>Objectives</h4>This retrospective study examined how a pharmacist-involved education program in a multidisciplinary team (PEMT) for oral mucositis (OM) affected head-and-neck cancer (HNC) patients receiving concurrent chemoradiotherapy (CCRT).<h4>Materials and methods</h4>Total samples data of 53 patients during the stipulated timeframe were retrospectively collected from electronic medical records from February 2017 to January 2019. We compared the presence/absence of OM (OM: yes/no) between patients with and without PEMT (PEMT: yes/no) as the primary endpoint and OM severity as the secondary endpoint. The following information was surveyed: age, gender, weight loss, steroid or immunosuppressant use, hematological values (albumin, white blood cell count, blood platelets, and neutrophils), cancer grade, primary cancer site, type and use of mouthwash and moisturizer, opioid use (yes/no, days until the start of opioid use, and dose, switch to tape), and length of hospital day (LOD). The two groups were compared using Fisher's exact test for qualitative data and the Mann-Whitney U test for quantitative data, and a significance level of p<0.05 was set.<h4>Results</h4>The group managed by PEMT had significantly lower weight loss and a significantly lower incidence of local anesthetic and opioid use and switch to tape compared with the group not managed by PEMT (p<0.05). The two groups showed no significant difference in OM (yes/no) or OM severity. The PEMT group had significantly shorter LOD at 57 (53-64) days compared with the non-PEMT group at 63.5 (57-68) days (p<0.05).<h4>Conclusions</h4>Our results showed that PEMT did not improve OM (yes/no) or OM severity in HNC patients undergoing CCRT. However, the PEMT group had a lower incidence of grades 3 and 4 OM than the non-PEMT group, although not significantly. In addition, PEMT contributed to oral pain relief and the lowering of the risk for OM by reduction in weight loss.Kensuke YoshidaYasumitsu KodamaYusuke TanakaKyongsun PakMarie SogaAkira ToyamaKouji KatsuraRitsuo TakagiPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 11, p e0260026 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Kensuke Yoshida Yasumitsu Kodama Yusuke Tanaka Kyongsun Pak Marie Soga Akira Toyama Kouji Katsura Ritsuo Takagi Pharmacist involved education program in a multidisciplinary team for oral mucositis: Its impact in head-and-neck cancer patients.
description	<h4>Objectives</h4>This retrospective study examined how a pharmacist-involved education program in a multidisciplinary team (PEMT) for oral mucositis (OM) affected head-and-neck cancer (HNC) patients receiving concurrent chemoradiotherapy (CCRT).<h4>Materials and methods</h4>Total samples data of 53 patients during the stipulated timeframe were retrospectively collected from electronic medical records from February 2017 to January 2019. We compared the presence/absence of OM (OM: yes/no) between patients with and without PEMT (PEMT: yes/no) as the primary endpoint and OM severity as the secondary endpoint. The following information was surveyed: age, gender, weight loss, steroid or immunosuppressant use, hematological values (albumin, white blood cell count, blood platelets, and neutrophils), cancer grade, primary cancer site, type and use of mouthwash and moisturizer, opioid use (yes/no, days until the start of opioid use, and dose, switch to tape), and length of hospital day (LOD). The two groups were compared using Fisher's exact test for qualitative data and the Mann-Whitney U test for quantitative data, and a significance level of p<0.05 was set.<h4>Results</h4>The group managed by PEMT had significantly lower weight loss and a significantly lower incidence of local anesthetic and opioid use and switch to tape compared with the group not managed by PEMT (p<0.05). The two groups showed no significant difference in OM (yes/no) or OM severity. The PEMT group had significantly shorter LOD at 57 (53-64) days compared with the non-PEMT group at 63.5 (57-68) days (p<0.05).<h4>Conclusions</h4>Our results showed that PEMT did not improve OM (yes/no) or OM severity in HNC patients undergoing CCRT. However, the PEMT group had a lower incidence of grades 3 and 4 OM than the non-PEMT group, although not significantly. In addition, PEMT contributed to oral pain relief and the lowering of the risk for OM by reduction in weight loss.
format	article
author	Kensuke Yoshida Yasumitsu Kodama Yusuke Tanaka Kyongsun Pak Marie Soga Akira Toyama Kouji Katsura Ritsuo Takagi
author_facet	Kensuke Yoshida Yasumitsu Kodama Yusuke Tanaka Kyongsun Pak Marie Soga Akira Toyama Kouji Katsura Ritsuo Takagi
author_sort	Kensuke Yoshida
title	Pharmacist involved education program in a multidisciplinary team for oral mucositis: Its impact in head-and-neck cancer patients.
title_short	Pharmacist involved education program in a multidisciplinary team for oral mucositis: Its impact in head-and-neck cancer patients.
title_full	Pharmacist involved education program in a multidisciplinary team for oral mucositis: Its impact in head-and-neck cancer patients.
title_fullStr	Pharmacist involved education program in a multidisciplinary team for oral mucositis: Its impact in head-and-neck cancer patients.
title_full_unstemmed	Pharmacist involved education program in a multidisciplinary team for oral mucositis: Its impact in head-and-neck cancer patients.
title_sort	pharmacist involved education program in a multidisciplinary team for oral mucositis: its impact in head-and-neck cancer patients.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/7a69c21990f8404ba8e9364f4896cc74
work_keys_str_mv	AT kensukeyoshida pharmacistinvolvededucationprograminamultidisciplinaryteamfororalmucositisitsimpactinheadandneckcancerpatients AT yasumitsukodama pharmacistinvolvededucationprograminamultidisciplinaryteamfororalmucositisitsimpactinheadandneckcancerpatients AT yusuketanaka pharmacistinvolvededucationprograminamultidisciplinaryteamfororalmucositisitsimpactinheadandneckcancerpatients AT kyongsunpak pharmacistinvolvededucationprograminamultidisciplinaryteamfororalmucositisitsimpactinheadandneckcancerpatients AT mariesoga pharmacistinvolvededucationprograminamultidisciplinaryteamfororalmucositisitsimpactinheadandneckcancerpatients AT akiratoyama pharmacistinvolvededucationprograminamultidisciplinaryteamfororalmucositisitsimpactinheadandneckcancerpatients AT koujikatsura pharmacistinvolvededucationprograminamultidisciplinaryteamfororalmucositisitsimpactinheadandneckcancerpatients AT ritsuotakagi pharmacistinvolvededucationprograminamultidisciplinaryteamfororalmucositisitsimpactinheadandneckcancerpatients
_version_	1718374535025131520

Pharmacist involved education program in a multidisciplinary team for oral mucositis: Its impact in head-and-neck cancer patients.

Ejemplares similares