Association between Milk Intake and Incident Stroke among Japanese Community Dwellers: The Iwate-KENCO Study

We aimed to evaluate the association between the milk consumption and incident stroke in a Japanese population, where milk consumption is lower than that of Western countries. In total, 14,121 participants (4253 men and 9868 women) aged 40–69 years, free from cardiovascular diseases (CVD) were prosp...

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Autores principales: Kozo Tanno, Yuki Yonekura, Nagako Okuda, Toru Kuribayashi, En Yabe, Megumi Tsubota-Utsugi, Shinichi Omama, Toshiyuki Onoda, Masaki Ohsawa, Kuniaki Ogasawara, Fumitaka Tanaka, Koichi Asahi, Ryo Itabashi, Shigeki Ito, Yasushi Ishigaki, Fumiaki Takahashi, Makoto Koshiyama, Ryohei Sasaki, Daisuke Fujimaki, Nobuyuki Takanashi, Eri Takusari, Kiyomi Sakata, Akira Okayama
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Publicado: MDPI AG 2021
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Acceso en línea:https://doaj.org/article/7a741c9c3d834e38806bae91a627e610
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spelling oai:doaj.org-article:7a741c9c3d834e38806bae91a627e6102021-11-25T18:33:59ZAssociation between Milk Intake and Incident Stroke among Japanese Community Dwellers: The Iwate-KENCO Study10.3390/nu131137812072-6643https://doaj.org/article/7a741c9c3d834e38806bae91a627e6102021-10-01T00:00:00Zhttps://www.mdpi.com/2072-6643/13/11/3781https://doaj.org/toc/2072-6643We aimed to evaluate the association between the milk consumption and incident stroke in a Japanese population, where milk consumption is lower than that of Western countries. In total, 14,121 participants (4253 men and 9868 women) aged 40–69 years, free from cardiovascular diseases (CVD) were prospectively followed for 10.7 years. Participants were categorized into four groups according to the milk intake frequency obtained from a brief-type self-administered diet questionnaire. The adjusted HRs of total stroke, ischemic stroke and haemorrhagic stroke associated with milk intake frequency were calculated using the Cox proportional hazards model. During the follow-up, 478 stroke cases were detected (208 men and 270 women). Compared to women with a milk intake of <2 cups/week, those with an intake of 7 to <12 cups/week had a significantly low risk of ischemic stroke in a model adjusting CVD risk factors; the HR (95% CI) was 0.53 (0.32–0.88). No significant associations were found in men. This study suggested that milk intake of 7 to <12 cups/week decreased the risk of ischemic stroke in Japanese women. Milk intake of about 1 to <2 cups/day may be effective in the primary prevention of ischemic stroke in a population with low milk intake.Kozo TannoYuki YonekuraNagako OkudaToru KuribayashiEn YabeMegumi Tsubota-UtsugiShinichi OmamaToshiyuki OnodaMasaki OhsawaKuniaki OgasawaraFumitaka TanakaKoichi AsahiRyo ItabashiShigeki ItoYasushi IshigakiFumiaki TakahashiMakoto KoshiyamaRyohei SasakiDaisuke FujimakiNobuyuki TakanashiEri TakusariKiyomi SakataAkira OkayamaMDPI AGarticlemilk intakestrokeprospective cohort studyJapanese populationNutrition. Foods and food supplyTX341-641ENNutrients, Vol 13, Iss 3781, p 3781 (2021)
institution DOAJ
collection DOAJ
language EN
topic milk intake
stroke
prospective cohort study
Japanese population
Nutrition. Foods and food supply
TX341-641
spellingShingle milk intake
stroke
prospective cohort study
Japanese population
Nutrition. Foods and food supply
TX341-641
Kozo Tanno
Yuki Yonekura
Nagako Okuda
Toru Kuribayashi
En Yabe
Megumi Tsubota-Utsugi
Shinichi Omama
Toshiyuki Onoda
Masaki Ohsawa
Kuniaki Ogasawara
Fumitaka Tanaka
Koichi Asahi
Ryo Itabashi
Shigeki Ito
Yasushi Ishigaki
Fumiaki Takahashi
Makoto Koshiyama
Ryohei Sasaki
Daisuke Fujimaki
Nobuyuki Takanashi
Eri Takusari
Kiyomi Sakata
Akira Okayama
Association between Milk Intake and Incident Stroke among Japanese Community Dwellers: The Iwate-KENCO Study
description We aimed to evaluate the association between the milk consumption and incident stroke in a Japanese population, where milk consumption is lower than that of Western countries. In total, 14,121 participants (4253 men and 9868 women) aged 40–69 years, free from cardiovascular diseases (CVD) were prospectively followed for 10.7 years. Participants were categorized into four groups according to the milk intake frequency obtained from a brief-type self-administered diet questionnaire. The adjusted HRs of total stroke, ischemic stroke and haemorrhagic stroke associated with milk intake frequency were calculated using the Cox proportional hazards model. During the follow-up, 478 stroke cases were detected (208 men and 270 women). Compared to women with a milk intake of <2 cups/week, those with an intake of 7 to <12 cups/week had a significantly low risk of ischemic stroke in a model adjusting CVD risk factors; the HR (95% CI) was 0.53 (0.32–0.88). No significant associations were found in men. This study suggested that milk intake of 7 to <12 cups/week decreased the risk of ischemic stroke in Japanese women. Milk intake of about 1 to <2 cups/day may be effective in the primary prevention of ischemic stroke in a population with low milk intake.
format article
author Kozo Tanno
Yuki Yonekura
Nagako Okuda
Toru Kuribayashi
En Yabe
Megumi Tsubota-Utsugi
Shinichi Omama
Toshiyuki Onoda
Masaki Ohsawa
Kuniaki Ogasawara
Fumitaka Tanaka
Koichi Asahi
Ryo Itabashi
Shigeki Ito
Yasushi Ishigaki
Fumiaki Takahashi
Makoto Koshiyama
Ryohei Sasaki
Daisuke Fujimaki
Nobuyuki Takanashi
Eri Takusari
Kiyomi Sakata
Akira Okayama
author_facet Kozo Tanno
Yuki Yonekura
Nagako Okuda
Toru Kuribayashi
En Yabe
Megumi Tsubota-Utsugi
Shinichi Omama
Toshiyuki Onoda
Masaki Ohsawa
Kuniaki Ogasawara
Fumitaka Tanaka
Koichi Asahi
Ryo Itabashi
Shigeki Ito
Yasushi Ishigaki
Fumiaki Takahashi
Makoto Koshiyama
Ryohei Sasaki
Daisuke Fujimaki
Nobuyuki Takanashi
Eri Takusari
Kiyomi Sakata
Akira Okayama
author_sort Kozo Tanno
title Association between Milk Intake and Incident Stroke among Japanese Community Dwellers: The Iwate-KENCO Study
title_short Association between Milk Intake and Incident Stroke among Japanese Community Dwellers: The Iwate-KENCO Study
title_full Association between Milk Intake and Incident Stroke among Japanese Community Dwellers: The Iwate-KENCO Study
title_fullStr Association between Milk Intake and Incident Stroke among Japanese Community Dwellers: The Iwate-KENCO Study
title_full_unstemmed Association between Milk Intake and Incident Stroke among Japanese Community Dwellers: The Iwate-KENCO Study
title_sort association between milk intake and incident stroke among japanese community dwellers: the iwate-kenco study
publisher MDPI AG
publishDate 2021
url https://doaj.org/article/7a741c9c3d834e38806bae91a627e610
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