Reduced sensitivity to immediate reward during decision-making in older than younger adults.

We examined whether older adults differ from younger adults in the degree to which they favor immediate over delayed rewards during decision-making. To examine the neural correlates of age-related differences in delay discounting we acquired functional MR images while participants made decisions bet...

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Autores principales:	Ben Eppinger, Leigh E Nystrom, Jonathan D Cohen
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2012
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/7a86f6768000488d911caf8206099104
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spelling	oai:doaj.org-article:7a86f6768000488d911caf82060991042021-11-18T07:17:35ZReduced sensitivity to immediate reward during decision-making in older than younger adults.1932-620310.1371/journal.pone.0036953https://doaj.org/article/7a86f6768000488d911caf82060991042012-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22655032/pdf/?tool=EBIhttps://doaj.org/toc/1932-6203We examined whether older adults differ from younger adults in the degree to which they favor immediate over delayed rewards during decision-making. To examine the neural correlates of age-related differences in delay discounting we acquired functional MR images while participants made decisions between smaller but sooner and larger but later monetary rewards. The behavioral results show age-related reductions in delay discounting. Less impulsive decision-making in older adults was associated with lower ventral striatal activations to immediate reward. Furthermore, older adults showed an overall higher percentage of delayed choices and reduced activity in the dorsal striatum than younger adults. This points to a reduced reward sensitivity of the dorsal striatum in older adults. Taken together, our findings indicate that less impulsive decision-making in older adults is due to a reduced sensitivity of striatal areas to reward. These age-related changes in reward sensitivity may result from transformations in dopaminergic neuromodulation with age.Ben EppingerLeigh E NystromJonathan D CohenPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 7, Iss 5, p e36953 (2012)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Ben Eppinger Leigh E Nystrom Jonathan D Cohen Reduced sensitivity to immediate reward during decision-making in older than younger adults.
description	We examined whether older adults differ from younger adults in the degree to which they favor immediate over delayed rewards during decision-making. To examine the neural correlates of age-related differences in delay discounting we acquired functional MR images while participants made decisions between smaller but sooner and larger but later monetary rewards. The behavioral results show age-related reductions in delay discounting. Less impulsive decision-making in older adults was associated with lower ventral striatal activations to immediate reward. Furthermore, older adults showed an overall higher percentage of delayed choices and reduced activity in the dorsal striatum than younger adults. This points to a reduced reward sensitivity of the dorsal striatum in older adults. Taken together, our findings indicate that less impulsive decision-making in older adults is due to a reduced sensitivity of striatal areas to reward. These age-related changes in reward sensitivity may result from transformations in dopaminergic neuromodulation with age.
format	article
author	Ben Eppinger Leigh E Nystrom Jonathan D Cohen
author_facet	Ben Eppinger Leigh E Nystrom Jonathan D Cohen
author_sort	Ben Eppinger
title	Reduced sensitivity to immediate reward during decision-making in older than younger adults.
title_short	Reduced sensitivity to immediate reward during decision-making in older than younger adults.
title_full	Reduced sensitivity to immediate reward during decision-making in older than younger adults.
title_fullStr	Reduced sensitivity to immediate reward during decision-making in older than younger adults.
title_full_unstemmed	Reduced sensitivity to immediate reward during decision-making in older than younger adults.
title_sort	reduced sensitivity to immediate reward during decision-making in older than younger adults.
publisher	Public Library of Science (PLoS)
publishDate	2012
url	https://doaj.org/article/7a86f6768000488d911caf8206099104
work_keys_str_mv	AT beneppinger reducedsensitivitytoimmediaterewardduringdecisionmakinginolderthanyoungeradults AT leighenystrom reducedsensitivitytoimmediaterewardduringdecisionmakinginolderthanyoungeradults AT jonathandcohen reducedsensitivitytoimmediaterewardduringdecisionmakinginolderthanyoungeradults
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Reduced sensitivity to immediate reward during decision-making in older than younger adults.

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