A conserved RNA structural motif for organizing topology within picornaviral internal ribosome entry sites
Picornaviruses use modular RNA domains in their internal ribosome entry sites (IRESs) for translation through non-canonical, cap-independent mechanisms. Here the authors report the crystal structure of domain V from the IRES of hepatitis A virus (HAV) ssRNA genome, suggesting that the functional hom...
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Auteurs principaux: | Deepak Koirala, Yaming Shao, Yelena Koldobskaya, James R. Fuller, Andrew M. Watkins, Sandip A. Shelke, Evgeny V. Pilipenko, Rhiju Das, Phoebe A. Rice, Joseph A. Piccirilli |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2019
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Accès en ligne: | https://doaj.org/article/7a89e6027bf4428f95ad4027eb511ff7 |
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