Analysis of the R1b-DF27 haplogroup shows that a large fraction of Iberian Y-chromosome lineages originated recently in situ
Abstract Haplogroup R1b-M269 comprises most Western European Y chromosomes; of its main branches, R1b-DF27 is by far the least known, and it appears to be highly prevalent only in Iberia. We have genotyped 1072 R1b-DF27 chromosomes for six additional SNPs and 17 Y-STRs in population samples from Spa...
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2017
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oai:doaj.org-article:7a8ef1a23c124a93b5c37fcc00af1c622021-12-02T16:06:57ZAnalysis of the R1b-DF27 haplogroup shows that a large fraction of Iberian Y-chromosome lineages originated recently in situ10.1038/s41598-017-07710-x2045-2322https://doaj.org/article/7a8ef1a23c124a93b5c37fcc00af1c622017-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-07710-xhttps://doaj.org/toc/2045-2322Abstract Haplogroup R1b-M269 comprises most Western European Y chromosomes; of its main branches, R1b-DF27 is by far the least known, and it appears to be highly prevalent only in Iberia. We have genotyped 1072 R1b-DF27 chromosomes for six additional SNPs and 17 Y-STRs in population samples from Spain, Portugal and France in order to further characterize this lineage and, in particular, to ascertain the time and place where it originated, as well as its subsequent dynamics. We found that R1b-DF27 is present in frequencies ~40% in Iberian populations and up to 70% in Basques, but it drops quickly to 6–20% in France. Overall, the age of R1b-DF27 is estimated at ~4,200 years ago, at the transition between the Neolithic and the Bronze Age, when the Y chromosome landscape of W Europe was thoroughly remodeled. In spite of its high frequency in Basques, Y-STR internal diversity of R1b-DF27 is lower there, and results in more recent age estimates; NE Iberia is the most likely place of origin of DF27. Subhaplogroup frequencies within R1b-DF27 are geographically structured, and show domains that are reminiscent of the pre-Roman Celtic/Iberian division, or of the medieval Christian kingdoms.Neus Solé-MorataPatricia VillaescusaCarla García-FernándezNeus Font-PorteriasMaría José IllescasLaura ValverdeFrancesca TassiSilvia GhirottoClaude FérecKaren RouaultSusana Jiménez-MorenoBegoña Martínez-JarretaMaria Fátima PinheiroMaría T. ZarrabeitiaÁngel CarracedoMarian M. de PancorboFrancesc CalafellNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-13 (2017) |
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Medicine R Science Q Neus Solé-Morata Patricia Villaescusa Carla García-Fernández Neus Font-Porterias María José Illescas Laura Valverde Francesca Tassi Silvia Ghirotto Claude Férec Karen Rouault Susana Jiménez-Moreno Begoña Martínez-Jarreta Maria Fátima Pinheiro María T. Zarrabeitia Ángel Carracedo Marian M. de Pancorbo Francesc Calafell Analysis of the R1b-DF27 haplogroup shows that a large fraction of Iberian Y-chromosome lineages originated recently in situ |
| description |
Abstract Haplogroup R1b-M269 comprises most Western European Y chromosomes; of its main branches, R1b-DF27 is by far the least known, and it appears to be highly prevalent only in Iberia. We have genotyped 1072 R1b-DF27 chromosomes for six additional SNPs and 17 Y-STRs in population samples from Spain, Portugal and France in order to further characterize this lineage and, in particular, to ascertain the time and place where it originated, as well as its subsequent dynamics. We found that R1b-DF27 is present in frequencies ~40% in Iberian populations and up to 70% in Basques, but it drops quickly to 6–20% in France. Overall, the age of R1b-DF27 is estimated at ~4,200 years ago, at the transition between the Neolithic and the Bronze Age, when the Y chromosome landscape of W Europe was thoroughly remodeled. In spite of its high frequency in Basques, Y-STR internal diversity of R1b-DF27 is lower there, and results in more recent age estimates; NE Iberia is the most likely place of origin of DF27. Subhaplogroup frequencies within R1b-DF27 are geographically structured, and show domains that are reminiscent of the pre-Roman Celtic/Iberian division, or of the medieval Christian kingdoms. |
| format |
article |
| author |
Neus Solé-Morata Patricia Villaescusa Carla García-Fernández Neus Font-Porterias María José Illescas Laura Valverde Francesca Tassi Silvia Ghirotto Claude Férec Karen Rouault Susana Jiménez-Moreno Begoña Martínez-Jarreta Maria Fátima Pinheiro María T. Zarrabeitia Ángel Carracedo Marian M. de Pancorbo Francesc Calafell |
| author_facet |
Neus Solé-Morata Patricia Villaescusa Carla García-Fernández Neus Font-Porterias María José Illescas Laura Valverde Francesca Tassi Silvia Ghirotto Claude Férec Karen Rouault Susana Jiménez-Moreno Begoña Martínez-Jarreta Maria Fátima Pinheiro María T. Zarrabeitia Ángel Carracedo Marian M. de Pancorbo Francesc Calafell |
| author_sort |
Neus Solé-Morata |
| title |
Analysis of the R1b-DF27 haplogroup shows that a large fraction of Iberian Y-chromosome lineages originated recently in situ |
| title_short |
Analysis of the R1b-DF27 haplogroup shows that a large fraction of Iberian Y-chromosome lineages originated recently in situ |
| title_full |
Analysis of the R1b-DF27 haplogroup shows that a large fraction of Iberian Y-chromosome lineages originated recently in situ |
| title_fullStr |
Analysis of the R1b-DF27 haplogroup shows that a large fraction of Iberian Y-chromosome lineages originated recently in situ |
| title_full_unstemmed |
Analysis of the R1b-DF27 haplogroup shows that a large fraction of Iberian Y-chromosome lineages originated recently in situ |
| title_sort |
analysis of the r1b-df27 haplogroup shows that a large fraction of iberian y-chromosome lineages originated recently in situ |
| publisher |
Nature Portfolio |
| publishDate |
2017 |
| url |
https://doaj.org/article/7a8ef1a23c124a93b5c37fcc00af1c62 |
| work_keys_str_mv |
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