Lineage-level divergence of copepod glycerol transporters and the emergence of isoform-specific trafficking regulation
Marc Catalán-Garcia et al. examine evolutionary divergence of aquaglyceroporins (GLPs) in copepods, observing that these genes are subject to high rates of gene duplication across species. They also report tissue- and sex-specific expression of GLP splice variants in the parasitic copepod, L. salmon...
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| Autores principales: | , , , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2021
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/7a8f56f6bd0a41bc8c88b4598476f82c |
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| Sumario: | Marc Catalán-Garcia et al. examine evolutionary divergence of aquaglyceroporins (GLPs) in copepods, observing that these genes are subject to high rates of gene duplication across species. They also report tissue- and sex-specific expression of GLP splice variants in the parasitic copepod, L. salmonis, that in turn exhibit PKA- or PKC-dependent changes in membrane trafficking. Altogether, these results suggest that mutations in GLP genes with precise regulation of intracellular tracking may be related to neofunctionalization in these species. |
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