Lineage-level divergence of copepod glycerol transporters and the emergence of isoform-specific trafficking regulation

Marc Catalán-Garcia et al. examine evolutionary divergence of aquaglyceroporins (GLPs) in copepods, observing that these genes are subject to high rates of gene duplication across species. They also report tissue- and sex-specific expression of GLP splice variants in the parasitic copepod, L. salmon...

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Autores principales:	Marc Catalán-García, François Chauvigné, Jon Anders Stavang, Frank Nilsen, Joan Cerdà, Roderick Nigel Finn
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/7a8f56f6bd0a41bc8c88b4598476f82c
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spelling	oai:doaj.org-article:7a8f56f6bd0a41bc8c88b4598476f82c2021-12-02T17:51:20ZLineage-level divergence of copepod glycerol transporters and the emergence of isoform-specific trafficking regulation10.1038/s42003-021-01921-92399-3642https://doaj.org/article/7a8f56f6bd0a41bc8c88b4598476f82c2021-05-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-01921-9https://doaj.org/toc/2399-3642Marc Catalán-Garcia et al. examine evolutionary divergence of aquaglyceroporins (GLPs) in copepods, observing that these genes are subject to high rates of gene duplication across species. They also report tissue- and sex-specific expression of GLP splice variants in the parasitic copepod, L. salmonis, that in turn exhibit PKA- or PKC-dependent changes in membrane trafficking. Altogether, these results suggest that mutations in GLP genes with precise regulation of intracellular tracking may be related to neofunctionalization in these species.Marc Catalán-GarcíaFrançois ChauvignéJon Anders StavangFrank NilsenJoan CerdàRoderick Nigel FinnNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Marc Catalán-García François Chauvigné Jon Anders Stavang Frank Nilsen Joan Cerdà Roderick Nigel Finn Lineage-level divergence of copepod glycerol transporters and the emergence of isoform-specific trafficking regulation
description	Marc Catalán-Garcia et al. examine evolutionary divergence of aquaglyceroporins (GLPs) in copepods, observing that these genes are subject to high rates of gene duplication across species. They also report tissue- and sex-specific expression of GLP splice variants in the parasitic copepod, L. salmonis, that in turn exhibit PKA- or PKC-dependent changes in membrane trafficking. Altogether, these results suggest that mutations in GLP genes with precise regulation of intracellular tracking may be related to neofunctionalization in these species.
format	article
author	Marc Catalán-García François Chauvigné Jon Anders Stavang Frank Nilsen Joan Cerdà Roderick Nigel Finn
author_facet	Marc Catalán-García François Chauvigné Jon Anders Stavang Frank Nilsen Joan Cerdà Roderick Nigel Finn
author_sort	Marc Catalán-García
title	Lineage-level divergence of copepod glycerol transporters and the emergence of isoform-specific trafficking regulation
title_short	Lineage-level divergence of copepod glycerol transporters and the emergence of isoform-specific trafficking regulation
title_full	Lineage-level divergence of copepod glycerol transporters and the emergence of isoform-specific trafficking regulation
title_fullStr	Lineage-level divergence of copepod glycerol transporters and the emergence of isoform-specific trafficking regulation
title_full_unstemmed	Lineage-level divergence of copepod glycerol transporters and the emergence of isoform-specific trafficking regulation
title_sort	lineage-level divergence of copepod glycerol transporters and the emergence of isoform-specific trafficking regulation
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/7a8f56f6bd0a41bc8c88b4598476f82c
work_keys_str_mv	AT marccatalangarcia lineageleveldivergenceofcopepodglyceroltransportersandtheemergenceofisoformspecifictraffickingregulation AT francoischauvigne lineageleveldivergenceofcopepodglyceroltransportersandtheemergenceofisoformspecifictraffickingregulation AT jonandersstavang lineageleveldivergenceofcopepodglyceroltransportersandtheemergenceofisoformspecifictraffickingregulation AT franknilsen lineageleveldivergenceofcopepodglyceroltransportersandtheemergenceofisoformspecifictraffickingregulation AT joancerda lineageleveldivergenceofcopepodglyceroltransportersandtheemergenceofisoformspecifictraffickingregulation AT rodericknigelfinn lineageleveldivergenceofcopepodglyceroltransportersandtheemergenceofisoformspecifictraffickingregulation
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Lineage-level divergence of copepod glycerol transporters and the emergence of isoform-specific trafficking regulation

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