Association between education and the risk of incident coronary heart disease among middle-aged and older Chinese: the Dongfeng-Tongji Cohort
Abstract Educational achievement was related to cardiovascular disease in some western populations, but prospective evidence on the relationship between education and the risk of incident coronary heart disease (CHD) in Asians is scarce. We aimed to explore this association and the potential modifyi...
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2017
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oai:doaj.org-article:7a93dfcdf10c494d8c2a77d93d5f36382021-12-02T15:06:13ZAssociation between education and the risk of incident coronary heart disease among middle-aged and older Chinese: the Dongfeng-Tongji Cohort10.1038/s41598-017-00880-82045-2322https://doaj.org/article/7a93dfcdf10c494d8c2a77d93d5f36382017-04-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-00880-8https://doaj.org/toc/2045-2322Abstract Educational achievement was related to cardiovascular disease in some western populations, but prospective evidence on the relationship between education and the risk of incident coronary heart disease (CHD) in Asians is scarce. We aimed to explore this association and the potential modifying effect of major CHD risk factors related to education in middle-aged and older Chinese adults. We included 18,551 participants with mean age 62.8 years at baseline between September 2008 and June 2010, and followed the population until October 2013. Cox proportional hazard models and log-binomial regression models were used for multivariate analyses. Compared with participants with low education, the adjusted hazard ratio (HR) and 95% confidence interval (95% CI) for incident CHD in those with high education was 0.89 (95% CI: 0.80, 0.98). In addition, such inverse association between education and the risk of incident CHD was more evident among individuals who were more than 60 years, physically active, overweight, and hypertension. Besides, decreases in the relative index of inequality with high education versus low education were from 0.83 to 0.76 for hypertension, from 0.85 to 0.82 for diabetes. In conclusion, education was inversely associated with the risk of incident CHD among middle-aged and older Chinese adults.Hao WangYu YuanLulu SongGaokun QiuXuefeng LaiLiangle YangYang XiaoLue ZhouHandong YangXiulou LiChengwei XuXiaomin ZhangMei-an HeTangchun WuNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-8 (2017) |
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Medicine R Science Q Hao Wang Yu Yuan Lulu Song Gaokun Qiu Xuefeng Lai Liangle Yang Yang Xiao Lue Zhou Handong Yang Xiulou Li Chengwei Xu Xiaomin Zhang Mei-an He Tangchun Wu Association between education and the risk of incident coronary heart disease among middle-aged and older Chinese: the Dongfeng-Tongji Cohort |
| description |
Abstract Educational achievement was related to cardiovascular disease in some western populations, but prospective evidence on the relationship between education and the risk of incident coronary heart disease (CHD) in Asians is scarce. We aimed to explore this association and the potential modifying effect of major CHD risk factors related to education in middle-aged and older Chinese adults. We included 18,551 participants with mean age 62.8 years at baseline between September 2008 and June 2010, and followed the population until October 2013. Cox proportional hazard models and log-binomial regression models were used for multivariate analyses. Compared with participants with low education, the adjusted hazard ratio (HR) and 95% confidence interval (95% CI) for incident CHD in those with high education was 0.89 (95% CI: 0.80, 0.98). In addition, such inverse association between education and the risk of incident CHD was more evident among individuals who were more than 60 years, physically active, overweight, and hypertension. Besides, decreases in the relative index of inequality with high education versus low education were from 0.83 to 0.76 for hypertension, from 0.85 to 0.82 for diabetes. In conclusion, education was inversely associated with the risk of incident CHD among middle-aged and older Chinese adults. |
| format |
article |
| author |
Hao Wang Yu Yuan Lulu Song Gaokun Qiu Xuefeng Lai Liangle Yang Yang Xiao Lue Zhou Handong Yang Xiulou Li Chengwei Xu Xiaomin Zhang Mei-an He Tangchun Wu |
| author_facet |
Hao Wang Yu Yuan Lulu Song Gaokun Qiu Xuefeng Lai Liangle Yang Yang Xiao Lue Zhou Handong Yang Xiulou Li Chengwei Xu Xiaomin Zhang Mei-an He Tangchun Wu |
| author_sort |
Hao Wang |
| title |
Association between education and the risk of incident coronary heart disease among middle-aged and older Chinese: the Dongfeng-Tongji Cohort |
| title_short |
Association between education and the risk of incident coronary heart disease among middle-aged and older Chinese: the Dongfeng-Tongji Cohort |
| title_full |
Association between education and the risk of incident coronary heart disease among middle-aged and older Chinese: the Dongfeng-Tongji Cohort |
| title_fullStr |
Association between education and the risk of incident coronary heart disease among middle-aged and older Chinese: the Dongfeng-Tongji Cohort |
| title_full_unstemmed |
Association between education and the risk of incident coronary heart disease among middle-aged and older Chinese: the Dongfeng-Tongji Cohort |
| title_sort |
association between education and the risk of incident coronary heart disease among middle-aged and older chinese: the dongfeng-tongji cohort |
| publisher |
Nature Portfolio |
| publishDate |
2017 |
| url |
https://doaj.org/article/7a93dfcdf10c494d8c2a77d93d5f3638 |
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