Association between tumor size and peritumoral brain edema in patients with convexity and parasagittal meningiomas.

<h4>Background and purpose</h4>Peritumoral brain edema (PTBE) is a common complication in meningioma and disruption of the tumor-brain barrier in meningioma is crucial for PTBE formation. To evaluate the association between meningioma size and PTBE, we measured meningioma volumes using t...

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Autores principales:	Chansub Shin, Jae Min Kim, Jin Hwan Cheong, Je Il Ryu, Yu Deok Won, Yong Ko, Myung-Hoon Han
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/7a940dc07a73444fbf934548bdf3ecc0
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spelling	oai:doaj.org-article:7a940dc07a73444fbf934548bdf3ecc02021-12-02T20:10:48ZAssociation between tumor size and peritumoral brain edema in patients with convexity and parasagittal meningiomas.1932-620310.1371/journal.pone.0252945https://doaj.org/article/7a940dc07a73444fbf934548bdf3ecc02021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0252945https://doaj.org/toc/1932-6203<h4>Background and purpose</h4>Peritumoral brain edema (PTBE) is a common complication in meningioma and disruption of the tumor-brain barrier in meningioma is crucial for PTBE formation. To evaluate the association between meningioma size and PTBE, we measured meningioma volumes using the 3D slicer in patients with convexity and parasagittal meningiomas.<h4>Methods</h4>Receiver operating characteristic curve analysis was used to determine the optimal cut-off meningioma volume values for predicting PTBE occurrence. Logistic regressions were used to estimate the odds ratios for PTBE occurrence in patients with convexity and parasagittal meningiomas according to several predictive factors.<h4>Results</h4>A total of 205 convexity or parasagittal meningioma patients with no other brain disease who underwent one or more contrast-enhanced brain MRIs were enrolled in this 10-year analysis in two hospitals. The optimal cut-off meningioma volume value for prediction of PTBE in all study patients was 13.953 cc (sensitivity = 76.1%; specificity = 92.5%). If a meningioma is assumed to be a complete sphere, 13.953 cc is about 2.987 cm in diameter.<h4>Conclusions</h4>Our study suggests a cut-off value of 3 cm meningioma diameter for prediction of PTBE in patients with convexity and parasagittal meningiomas. We believe that we have revealed why the meningioma diameter of 3 cm is clinically meaningful.Chansub ShinJae Min KimJin Hwan CheongJe Il RyuYu Deok WonYong KoMyung-Hoon HanPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 6, p e0252945 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Chansub Shin Jae Min Kim Jin Hwan Cheong Je Il Ryu Yu Deok Won Yong Ko Myung-Hoon Han Association between tumor size and peritumoral brain edema in patients with convexity and parasagittal meningiomas.
description	<h4>Background and purpose</h4>Peritumoral brain edema (PTBE) is a common complication in meningioma and disruption of the tumor-brain barrier in meningioma is crucial for PTBE formation. To evaluate the association between meningioma size and PTBE, we measured meningioma volumes using the 3D slicer in patients with convexity and parasagittal meningiomas.<h4>Methods</h4>Receiver operating characteristic curve analysis was used to determine the optimal cut-off meningioma volume values for predicting PTBE occurrence. Logistic regressions were used to estimate the odds ratios for PTBE occurrence in patients with convexity and parasagittal meningiomas according to several predictive factors.<h4>Results</h4>A total of 205 convexity or parasagittal meningioma patients with no other brain disease who underwent one or more contrast-enhanced brain MRIs were enrolled in this 10-year analysis in two hospitals. The optimal cut-off meningioma volume value for prediction of PTBE in all study patients was 13.953 cc (sensitivity = 76.1%; specificity = 92.5%). If a meningioma is assumed to be a complete sphere, 13.953 cc is about 2.987 cm in diameter.<h4>Conclusions</h4>Our study suggests a cut-off value of 3 cm meningioma diameter for prediction of PTBE in patients with convexity and parasagittal meningiomas. We believe that we have revealed why the meningioma diameter of 3 cm is clinically meaningful.
format	article
author	Chansub Shin Jae Min Kim Jin Hwan Cheong Je Il Ryu Yu Deok Won Yong Ko Myung-Hoon Han
author_facet	Chansub Shin Jae Min Kim Jin Hwan Cheong Je Il Ryu Yu Deok Won Yong Ko Myung-Hoon Han
author_sort	Chansub Shin
title	Association between tumor size and peritumoral brain edema in patients with convexity and parasagittal meningiomas.
title_short	Association between tumor size and peritumoral brain edema in patients with convexity and parasagittal meningiomas.
title_full	Association between tumor size and peritumoral brain edema in patients with convexity and parasagittal meningiomas.
title_fullStr	Association between tumor size and peritumoral brain edema in patients with convexity and parasagittal meningiomas.
title_full_unstemmed	Association between tumor size and peritumoral brain edema in patients with convexity and parasagittal meningiomas.
title_sort	association between tumor size and peritumoral brain edema in patients with convexity and parasagittal meningiomas.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/7a940dc07a73444fbf934548bdf3ecc0
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Association between tumor size and peritumoral brain edema in patients with convexity and parasagittal meningiomas.

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