A systematic literature review of patient perspectives of barriers and facilitators to access, adherence, stigma, and persistence to treatment for substance use disorder

Introduction: The opioid crisis has left a devastating impact on the United States (U.S.) for over 20 years. The over-prescribing of opioid medications and availability of illicit opioids have contributed to the U.S. opioid epidemic. Given the complexity of the epidemic, substance use disorder, and...

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Autores principales:	Alina Cernasev, Kenneth C. Hohmeier, Kelsey Frederick, Hilary Jasmin, Justin Gatwood
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	Systematic literature review Opioid use disorder Methadone Buprenorphine Patient Qualitative Pharmacy and materia medica RS1-441
Acceso en línea:	https://doaj.org/article/7a9a1ce49bee4c29a098a82975975ac0
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spelling	oai:doaj.org-article:7a9a1ce49bee4c29a098a82975975ac02021-11-04T04:45:13ZA systematic literature review of patient perspectives of barriers and facilitators to access, adherence, stigma, and persistence to treatment for substance use disorder2667-276610.1016/j.rcsop.2021.100029https://doaj.org/article/7a9a1ce49bee4c29a098a82975975ac02021-06-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2667276621000299https://doaj.org/toc/2667-2766Introduction: The opioid crisis has left a devastating impact on the United States (U.S.) for over 20 years. The over-prescribing of opioid medications and availability of illicit opioids have contributed to the U.S. opioid epidemic. Given the complexity of the epidemic, substance use disorder, and its treatment, there is an urgent need for a thorough review of the qualitative literature which has captured the patient's experiences Such patient-derived qualitative data on lived experiences and perspectives may allow researchers, clinicians, and policy makers to glean new insights into addressing this epidemic. Objectives: The objective of this paper is to present a systematic literature review of the existing U.S. qualitative research and provide a patient perspective on medications for opioid use disorder (MOUD), including barriers and facilitators to MOUD use. Methods: In November 2019, four electronic databases (PubMed, CINAHL, Scopus, and Web of Science) were searched by a medical librarian using a combination of keywords, Medical Subject Headings (MeSH), and/or CINAHL subject headings. 8766 results were imported into EndNote, then duplicate records were removed, leaving a total of 4722 articles. The unique records were imported into Rayyan QCRI an online platform designed to expedite screening. Blinded screening was undertaken in duplicate by four reviewers. Two researchers abstracted all the articles and used thematic analysis. Results: The screening in the abstract phase excluded 4681 results, leaving 41 studies for full-text screening to determine their eligibility for inclusion in the review. After screening, 21 articles were included in the study and the analysis is based on these articles Common themes across studies included stigmatization, perceived barriers to MOUD, and MOUD treatment deserts and provider shortages. Conclusions: Qualitative research studies conducted to date have uncovered substantial MOUD treatment barriers which are both social and structural in nature. Such barriers to treatment may serve to exacerbate the current epidemic and must be taken into consideration in designing policy and treatment solutions for patients with OUD.Alina CernasevKenneth C. HohmeierKelsey FrederickHilary JasminJustin GatwoodElsevierarticleSystematic literature reviewOpioid use disorderMethadoneBuprenorphinePatientQualitativePharmacy and materia medicaRS1-441ENExploratory Research in Clinical and Social Pharmacy, Vol 2, Iss , Pp 100029- (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Systematic literature review Opioid use disorder Methadone Buprenorphine Patient Qualitative Pharmacy and materia medica RS1-441
spellingShingle	Systematic literature review Opioid use disorder Methadone Buprenorphine Patient Qualitative Pharmacy and materia medica RS1-441 Alina Cernasev Kenneth C. Hohmeier Kelsey Frederick Hilary Jasmin Justin Gatwood A systematic literature review of patient perspectives of barriers and facilitators to access, adherence, stigma, and persistence to treatment for substance use disorder
description	Introduction: The opioid crisis has left a devastating impact on the United States (U.S.) for over 20 years. The over-prescribing of opioid medications and availability of illicit opioids have contributed to the U.S. opioid epidemic. Given the complexity of the epidemic, substance use disorder, and its treatment, there is an urgent need for a thorough review of the qualitative literature which has captured the patient's experiences Such patient-derived qualitative data on lived experiences and perspectives may allow researchers, clinicians, and policy makers to glean new insights into addressing this epidemic. Objectives: The objective of this paper is to present a systematic literature review of the existing U.S. qualitative research and provide a patient perspective on medications for opioid use disorder (MOUD), including barriers and facilitators to MOUD use. Methods: In November 2019, four electronic databases (PubMed, CINAHL, Scopus, and Web of Science) were searched by a medical librarian using a combination of keywords, Medical Subject Headings (MeSH), and/or CINAHL subject headings. 8766 results were imported into EndNote, then duplicate records were removed, leaving a total of 4722 articles. The unique records were imported into Rayyan QCRI an online platform designed to expedite screening. Blinded screening was undertaken in duplicate by four reviewers. Two researchers abstracted all the articles and used thematic analysis. Results: The screening in the abstract phase excluded 4681 results, leaving 41 studies for full-text screening to determine their eligibility for inclusion in the review. After screening, 21 articles were included in the study and the analysis is based on these articles Common themes across studies included stigmatization, perceived barriers to MOUD, and MOUD treatment deserts and provider shortages. Conclusions: Qualitative research studies conducted to date have uncovered substantial MOUD treatment barriers which are both social and structural in nature. Such barriers to treatment may serve to exacerbate the current epidemic and must be taken into consideration in designing policy and treatment solutions for patients with OUD.
format	article
author	Alina Cernasev Kenneth C. Hohmeier Kelsey Frederick Hilary Jasmin Justin Gatwood
author_facet	Alina Cernasev Kenneth C. Hohmeier Kelsey Frederick Hilary Jasmin Justin Gatwood
author_sort	Alina Cernasev
title	A systematic literature review of patient perspectives of barriers and facilitators to access, adherence, stigma, and persistence to treatment for substance use disorder
title_short	A systematic literature review of patient perspectives of barriers and facilitators to access, adherence, stigma, and persistence to treatment for substance use disorder
title_full	A systematic literature review of patient perspectives of barriers and facilitators to access, adherence, stigma, and persistence to treatment for substance use disorder
title_fullStr	A systematic literature review of patient perspectives of barriers and facilitators to access, adherence, stigma, and persistence to treatment for substance use disorder
title_full_unstemmed	A systematic literature review of patient perspectives of barriers and facilitators to access, adherence, stigma, and persistence to treatment for substance use disorder
title_sort	systematic literature review of patient perspectives of barriers and facilitators to access, adherence, stigma, and persistence to treatment for substance use disorder
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/7a9a1ce49bee4c29a098a82975975ac0
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A systematic literature review of patient perspectives of barriers and facilitators to access, adherence, stigma, and persistence to treatment for substance use disorder

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