Bacterial RadA is a DnaB-type helicase interacting with RecA to promote bidirectional D-loop extension

Bacterial homologous recombination involves the actions of RadA and RecA to promote single-stranded DNA integration. Here the authors report the structure of RadA fromStreptococcus pneumoniaeand demonstrate that it acts as a hexameric DnaB-type helicase.

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Detalles Bibliográficos
Autores principales: Léa Marie, Chiara Rapisarda, Violette Morales, Mathieu Bergé, Thomas Perry, Anne-Lise Soulet, Clémence Gruget, Han Remaut, Rémi Fronzes, Patrice Polard
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/7a9b00b90f3f4b7b84f74f5b83a1ec17
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Sumario:Bacterial homologous recombination involves the actions of RadA and RecA to promote single-stranded DNA integration. Here the authors report the structure of RadA fromStreptococcus pneumoniaeand demonstrate that it acts as a hexameric DnaB-type helicase.