Bacterial RadA is a DnaB-type helicase interacting with RecA to promote bidirectional D-loop extension

Bacterial homologous recombination involves the actions of RadA and RecA to promote single-stranded DNA integration. Here the authors report the structure of RadA fromStreptococcus pneumoniaeand demonstrate that it acts as a hexameric DnaB-type helicase.

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Auteurs principaux: Léa Marie, Chiara Rapisarda, Violette Morales, Mathieu Bergé, Thomas Perry, Anne-Lise Soulet, Clémence Gruget, Han Remaut, Rémi Fronzes, Patrice Polard
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Langue:EN
Publié: Nature Portfolio 2017
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Accès en ligne:https://doaj.org/article/7a9b00b90f3f4b7b84f74f5b83a1ec17
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spelling oai:doaj.org-article:7a9b00b90f3f4b7b84f74f5b83a1ec172021-12-02T14:42:19ZBacterial RadA is a DnaB-type helicase interacting with RecA to promote bidirectional D-loop extension10.1038/ncomms156382041-1723https://doaj.org/article/7a9b00b90f3f4b7b84f74f5b83a1ec172017-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms15638https://doaj.org/toc/2041-1723Bacterial homologous recombination involves the actions of RadA and RecA to promote single-stranded DNA integration. Here the authors report the structure of RadA fromStreptococcus pneumoniaeand demonstrate that it acts as a hexameric DnaB-type helicase.Léa MarieChiara RapisardaViolette MoralesMathieu BergéThomas PerryAnne-Lise SouletClémence GrugetHan RemautRémi FronzesPatrice PolardNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Léa Marie
Chiara Rapisarda
Violette Morales
Mathieu Bergé
Thomas Perry
Anne-Lise Soulet
Clémence Gruget
Han Remaut
Rémi Fronzes
Patrice Polard
Bacterial RadA is a DnaB-type helicase interacting with RecA to promote bidirectional D-loop extension
description Bacterial homologous recombination involves the actions of RadA and RecA to promote single-stranded DNA integration. Here the authors report the structure of RadA fromStreptococcus pneumoniaeand demonstrate that it acts as a hexameric DnaB-type helicase.
format article
author Léa Marie
Chiara Rapisarda
Violette Morales
Mathieu Bergé
Thomas Perry
Anne-Lise Soulet
Clémence Gruget
Han Remaut
Rémi Fronzes
Patrice Polard
author_facet Léa Marie
Chiara Rapisarda
Violette Morales
Mathieu Bergé
Thomas Perry
Anne-Lise Soulet
Clémence Gruget
Han Remaut
Rémi Fronzes
Patrice Polard
author_sort Léa Marie
title Bacterial RadA is a DnaB-type helicase interacting with RecA to promote bidirectional D-loop extension
title_short Bacterial RadA is a DnaB-type helicase interacting with RecA to promote bidirectional D-loop extension
title_full Bacterial RadA is a DnaB-type helicase interacting with RecA to promote bidirectional D-loop extension
title_fullStr Bacterial RadA is a DnaB-type helicase interacting with RecA to promote bidirectional D-loop extension
title_full_unstemmed Bacterial RadA is a DnaB-type helicase interacting with RecA to promote bidirectional D-loop extension
title_sort bacterial rada is a dnab-type helicase interacting with reca to promote bidirectional d-loop extension
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/7a9b00b90f3f4b7b84f74f5b83a1ec17
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