Bacterial RadA is a DnaB-type helicase interacting with RecA to promote bidirectional D-loop extension

Bacterial homologous recombination involves the actions of RadA and RecA to promote single-stranded DNA integration. Here the authors report the structure of RadA fromStreptococcus pneumoniaeand demonstrate that it acts as a hexameric DnaB-type helicase.

Guardado en:
Detalles Bibliográficos
Autores principales: Léa Marie, Chiara Rapisarda, Violette Morales, Mathieu Bergé, Thomas Perry, Anne-Lise Soulet, Clémence Gruget, Han Remaut, Rémi Fronzes, Patrice Polard
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Q
Acceso en línea:https://doaj.org/article/7a9b00b90f3f4b7b84f74f5b83a1ec17
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:7a9b00b90f3f4b7b84f74f5b83a1ec17
record_format dspace
spelling oai:doaj.org-article:7a9b00b90f3f4b7b84f74f5b83a1ec172021-12-02T14:42:19ZBacterial RadA is a DnaB-type helicase interacting with RecA to promote bidirectional D-loop extension10.1038/ncomms156382041-1723https://doaj.org/article/7a9b00b90f3f4b7b84f74f5b83a1ec172017-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms15638https://doaj.org/toc/2041-1723Bacterial homologous recombination involves the actions of RadA and RecA to promote single-stranded DNA integration. Here the authors report the structure of RadA fromStreptococcus pneumoniaeand demonstrate that it acts as a hexameric DnaB-type helicase.Léa MarieChiara RapisardaViolette MoralesMathieu BergéThomas PerryAnne-Lise SouletClémence GrugetHan RemautRémi FronzesPatrice PolardNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Léa Marie
Chiara Rapisarda
Violette Morales
Mathieu Bergé
Thomas Perry
Anne-Lise Soulet
Clémence Gruget
Han Remaut
Rémi Fronzes
Patrice Polard
Bacterial RadA is a DnaB-type helicase interacting with RecA to promote bidirectional D-loop extension
description Bacterial homologous recombination involves the actions of RadA and RecA to promote single-stranded DNA integration. Here the authors report the structure of RadA fromStreptococcus pneumoniaeand demonstrate that it acts as a hexameric DnaB-type helicase.
format article
author Léa Marie
Chiara Rapisarda
Violette Morales
Mathieu Bergé
Thomas Perry
Anne-Lise Soulet
Clémence Gruget
Han Remaut
Rémi Fronzes
Patrice Polard
author_facet Léa Marie
Chiara Rapisarda
Violette Morales
Mathieu Bergé
Thomas Perry
Anne-Lise Soulet
Clémence Gruget
Han Remaut
Rémi Fronzes
Patrice Polard
author_sort Léa Marie
title Bacterial RadA is a DnaB-type helicase interacting with RecA to promote bidirectional D-loop extension
title_short Bacterial RadA is a DnaB-type helicase interacting with RecA to promote bidirectional D-loop extension
title_full Bacterial RadA is a DnaB-type helicase interacting with RecA to promote bidirectional D-loop extension
title_fullStr Bacterial RadA is a DnaB-type helicase interacting with RecA to promote bidirectional D-loop extension
title_full_unstemmed Bacterial RadA is a DnaB-type helicase interacting with RecA to promote bidirectional D-loop extension
title_sort bacterial rada is a dnab-type helicase interacting with reca to promote bidirectional d-loop extension
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/7a9b00b90f3f4b7b84f74f5b83a1ec17
work_keys_str_mv AT leamarie bacterialradaisadnabtypehelicaseinteractingwithrecatopromotebidirectionaldloopextension
AT chiararapisarda bacterialradaisadnabtypehelicaseinteractingwithrecatopromotebidirectionaldloopextension
AT violettemorales bacterialradaisadnabtypehelicaseinteractingwithrecatopromotebidirectionaldloopextension
AT mathieuberge bacterialradaisadnabtypehelicaseinteractingwithrecatopromotebidirectionaldloopextension
AT thomasperry bacterialradaisadnabtypehelicaseinteractingwithrecatopromotebidirectionaldloopextension
AT annelisesoulet bacterialradaisadnabtypehelicaseinteractingwithrecatopromotebidirectionaldloopextension
AT clemencegruget bacterialradaisadnabtypehelicaseinteractingwithrecatopromotebidirectionaldloopextension
AT hanremaut bacterialradaisadnabtypehelicaseinteractingwithrecatopromotebidirectionaldloopextension
AT remifronzes bacterialradaisadnabtypehelicaseinteractingwithrecatopromotebidirectionaldloopextension
AT patricepolard bacterialradaisadnabtypehelicaseinteractingwithrecatopromotebidirectionaldloopextension
_version_ 1718389759070437376