Insulin-like growth factor-1 signaling regulates miRNA expression in MCF-7 breast cancer cell line.

Insulin-like growth factor-1 signaling regulates miRNA expression in MCF-7 breast cancer cell line.

In breast carcinomas, increased levels of insulin-like growth factor 1 (IGF-1) can act as a mitogen to augment tumorigenesis through the regulation of MAPK and AKT signaling pathways. Signaling through these two pathways allows IGF-1 to employ mechanisms that favor proliferation and cellular surviva...

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Autores principales: Elizabeth C Martin, Melyssa R Bratton, Yun Zhu, Lyndsay V Rhodes, Syreeta L Tilghman, Bridgette M Collins-Burow, Matthew E Burow
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/7aa4bd7ccd8044ce84fe440ce14cba74
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