JunB regulates homeostasis and suppressive functions of effector regulatory T cells
Regulatory T (Treg) cells need to be differentiated into effector Treg (eTreg), with the transcription factor IRF4 implicated during this process. Here the authors show that an AP-1 family transcription factor, JunB, is expressed in eTreg to promote the IRF4 transcription program, and regulate eTreg...
Guardado en:
Autores principales: | Shin-ichi Koizumi, Daiki Sasaki, Tsung-Han Hsieh, Naoyuki Taira, Nana Arakaki, Shinichi Yamasaki, Ke Wang, Shukla Sarkar, Hiroki Shirahata, Mio Miyagi, Hiroki Ishikawa |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
|
Materias: | |
Acceso en línea: | https://doaj.org/article/7aa833cf71e14ed6b77048af37da10b6 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
JunB is essential for IL-23-dependent pathogenicity of Th17 cells
por: Zafrul Hasan, et al.
Publicado: (2017) -
JunB defines functional and structural integrity of the epidermo-pilosebaceous unit in the skin
por: Karmveer Singh, et al.
Publicado: (2018) -
JunB promotes Th17 cell identity and restrains alternative CD4+ T-cell programs during inflammation
por: Tiffany M. Carr, et al.
Publicado: (2017) -
Activation of JUN in fibroblasts promotes pro-fibrotic programme and modulates protective immunity
por: Lu Cui, et al.
Publicado: (2020) -
Nota Editorial Edição 2017, v. 15, n. 1 (jan./jun.)
por: Luiz Andrei Gonçalves Pereira, et al.
Publicado: (2017)