JunB regulates homeostasis and suppressive functions of effector regulatory T cells

Regulatory T (Treg) cells need to be differentiated into effector Treg (eTreg), with the transcription factor IRF4 implicated during this process. Here the authors show that an AP-1 family transcription factor, JunB, is expressed in eTreg to promote the IRF4 transcription program, and regulate eTreg...

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Autores principales: Shin-ichi Koizumi, Daiki Sasaki, Tsung-Han Hsieh, Naoyuki Taira, Nana Arakaki, Shinichi Yamasaki, Ke Wang, Shukla Sarkar, Hiroki Shirahata, Mio Miyagi, Hiroki Ishikawa
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/7aa833cf71e14ed6b77048af37da10b6
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