Phosphorylation of Lamin A/C at serine 22 modulates Nav1.5 function
Abstract Variants in the LMNA gene, which encodes for Lamin A/C, are associated with cardiac conduction disease (CCD). We previously reported that Lamin A/C variants p.R545H and p.A287Lfs*193, which were identified in CCD patients, decreased peak INa in HEK‐293 cells expressing Nav1.5. Decreased pea...
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| Auteurs principaux: | , , , , , |
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| Format: | article |
| Langue: | EN |
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Wiley
2021
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| Accès en ligne: | https://doaj.org/article/7aaf40cbff3446268244b82cff02bd1c |
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