Clinical Characteristics and Empirical Research Model of Infectious Mononucleosis Complicated with Mycoplasma pneumoniae or/and Cytomegalovirus Infection

To study the clinical features of infectious mononucleosis (IM) caused by Epstein-Barr virus (EBV) mixed with Mycoplasma pneumonia (MP) or/and cytomegalovirus (CMV)infection, collected 201 hospitalized children who met the IM diagnostic criteria, the clinical manifestations, laboratory tests, compli...

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Autores principales: Jie Cai, Liping Yuan, Hui Gao, Bo Hu, Ming Gui
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Lenguaje:EN
Publicado: Hindawi Limited 2021
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Acceso en línea:https://doaj.org/article/7ab1d63580944b0cabf2cd29fb687f41
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spelling oai:doaj.org-article:7ab1d63580944b0cabf2cd29fb687f412021-11-22T01:11:07ZClinical Characteristics and Empirical Research Model of Infectious Mononucleosis Complicated with Mycoplasma pneumoniae or/and Cytomegalovirus Infection1748-671810.1155/2021/2867913https://doaj.org/article/7ab1d63580944b0cabf2cd29fb687f412021-01-01T00:00:00Zhttp://dx.doi.org/10.1155/2021/2867913https://doaj.org/toc/1748-6718To study the clinical features of infectious mononucleosis (IM) caused by Epstein-Barr virus (EBV) mixed with Mycoplasma pneumonia (MP) or/and cytomegalovirus (CMV)infection, collected 201 hospitalized children who met the IM diagnostic criteria, the clinical manifestations, laboratory tests, complications, treatment, and outcome were compared among EBV infection alone and EBV mixed with MP or/and CMV infection. Most of the children with IM were preschoolers, more frequently occurred in boys than girls. EBV patients with MP had the longest duration of fever. When mixed pathogen infections were involved, the white blood cell count of preschool children was significantly increased, while splenomegaly was more common in older children. In the cases of EBV infection alone, abnormal liver function was positively correlated with age (P=0.044). Mixed pathogen infections were more common in children with IM, occurring in all age groups, and some clinical characteristics were related to the age of onset and the pathogen of the infection.Jie CaiLiping YuanHui GaoBo HuMing GuiHindawi LimitedarticleComputer applications to medicine. Medical informaticsR858-859.7ENComputational and Mathematical Methods in Medicine, Vol 2021 (2021)
institution DOAJ
collection DOAJ
language EN
topic Computer applications to medicine. Medical informatics
R858-859.7
spellingShingle Computer applications to medicine. Medical informatics
R858-859.7
Jie Cai
Liping Yuan
Hui Gao
Bo Hu
Ming Gui
Clinical Characteristics and Empirical Research Model of Infectious Mononucleosis Complicated with Mycoplasma pneumoniae or/and Cytomegalovirus Infection
description To study the clinical features of infectious mononucleosis (IM) caused by Epstein-Barr virus (EBV) mixed with Mycoplasma pneumonia (MP) or/and cytomegalovirus (CMV)infection, collected 201 hospitalized children who met the IM diagnostic criteria, the clinical manifestations, laboratory tests, complications, treatment, and outcome were compared among EBV infection alone and EBV mixed with MP or/and CMV infection. Most of the children with IM were preschoolers, more frequently occurred in boys than girls. EBV patients with MP had the longest duration of fever. When mixed pathogen infections were involved, the white blood cell count of preschool children was significantly increased, while splenomegaly was more common in older children. In the cases of EBV infection alone, abnormal liver function was positively correlated with age (P=0.044). Mixed pathogen infections were more common in children with IM, occurring in all age groups, and some clinical characteristics were related to the age of onset and the pathogen of the infection.
format article
author Jie Cai
Liping Yuan
Hui Gao
Bo Hu
Ming Gui
author_facet Jie Cai
Liping Yuan
Hui Gao
Bo Hu
Ming Gui
author_sort Jie Cai
title Clinical Characteristics and Empirical Research Model of Infectious Mononucleosis Complicated with Mycoplasma pneumoniae or/and Cytomegalovirus Infection
title_short Clinical Characteristics and Empirical Research Model of Infectious Mononucleosis Complicated with Mycoplasma pneumoniae or/and Cytomegalovirus Infection
title_full Clinical Characteristics and Empirical Research Model of Infectious Mononucleosis Complicated with Mycoplasma pneumoniae or/and Cytomegalovirus Infection
title_fullStr Clinical Characteristics and Empirical Research Model of Infectious Mononucleosis Complicated with Mycoplasma pneumoniae or/and Cytomegalovirus Infection
title_full_unstemmed Clinical Characteristics and Empirical Research Model of Infectious Mononucleosis Complicated with Mycoplasma pneumoniae or/and Cytomegalovirus Infection
title_sort clinical characteristics and empirical research model of infectious mononucleosis complicated with mycoplasma pneumoniae or/and cytomegalovirus infection
publisher Hindawi Limited
publishDate 2021
url https://doaj.org/article/7ab1d63580944b0cabf2cd29fb687f41
work_keys_str_mv AT jiecai clinicalcharacteristicsandempiricalresearchmodelofinfectiousmononucleosiscomplicatedwithmycoplasmapneumoniaeorandcytomegalovirusinfection
AT lipingyuan clinicalcharacteristicsandempiricalresearchmodelofinfectiousmononucleosiscomplicatedwithmycoplasmapneumoniaeorandcytomegalovirusinfection
AT huigao clinicalcharacteristicsandempiricalresearchmodelofinfectiousmononucleosiscomplicatedwithmycoplasmapneumoniaeorandcytomegalovirusinfection
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