Enhanced Mucosal Immune Responses to HIV Virus-Like Particles Containing a Membrane-Anchored Adjuvant

Enhanced Mucosal Immune Responses to HIV Virus-Like Particles Containing a Membrane-Anchored Adjuvant

ABSTRACT Previously, a modified HIV Env protein with a heterologous membrane anchor was found to be incorporated into HIV virus-like particles (VLPs) at 10-fold-higher levels than those of unmodified Env. To further improve the immunogenicity of such VLPs, membrane-anchored forms of bacterial flagel...

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Autores principales: Elena V. Vassilieva, Bao-Zhong Wang, Andrei N. Vzorov, Li Wang, Ying-Chun Wang, Jadranka Bozja, Rui Xu, Richard W. Compans
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2011
Materias:
Microbiology
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Acceso en línea:https://doaj.org/article/7abd3b4a8c744161b498d41ecd04b850
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