Enhanced Mucosal Immune Responses to HIV Virus-Like Particles Containing a Membrane-Anchored Adjuvant
ABSTRACT Previously, a modified HIV Env protein with a heterologous membrane anchor was found to be incorporated into HIV virus-like particles (VLPs) at 10-fold-higher levels than those of unmodified Env. To further improve the immunogenicity of such VLPs, membrane-anchored forms of bacterial flagel...
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| Main Authors: | , , , , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
American Society for Microbiology
2011
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| Subjects: | |
| Online Access: | https://doaj.org/article/7abd3b4a8c744161b498d41ecd04b850 |
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