The evaluation of a web-based tool for measuring the uncorrected visual acuity and refractive error in keratoconus eyes: A method comparison study.

<h4>Purpose</h4>To evaluate the outcome of a web-based digital assessment of visual acuity and refractive error, compared to a conventional supervised assessment, in keratoconus patients with complex refractive errors.<h4>Material and methods</h4>Keratoconus patients, aged 18...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Marc B Muijzer, Janneau L J Claessens, Francesco Cassano, Daniel A Godefrooij, Yves F D M Prevoo, Robert P L Wisse
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
Materias:
R
Q
Acceso en línea:https://doaj.org/article/7adc57127f7e4f72a8012387bf0aae9e
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:7adc57127f7e4f72a8012387bf0aae9e
record_format dspace
spelling oai:doaj.org-article:7adc57127f7e4f72a8012387bf0aae9e2021-12-02T20:17:50ZThe evaluation of a web-based tool for measuring the uncorrected visual acuity and refractive error in keratoconus eyes: A method comparison study.1932-620310.1371/journal.pone.0256087https://doaj.org/article/7adc57127f7e4f72a8012387bf0aae9e2021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0256087https://doaj.org/toc/1932-6203<h4>Purpose</h4>To evaluate the outcome of a web-based digital assessment of visual acuity and refractive error, compared to a conventional supervised assessment, in keratoconus patients with complex refractive errors.<h4>Material and methods</h4>Keratoconus patients, aged 18 to 40, with a refractive error between -6 and +4 diopters were considered eligible. An uncorrected visual acuity and an assessment of refractive error was taken web-based (index test) and by manifest refraction (reference test) by an optometrist. Corrected visual acuity was assessed with the prescription derived from both the web-based tool and the manifest refraction. Non-inferiority was defined as the 95% limits-of-agreement (95%LoA) of the differences in spherical equivalent between the index and reference test not exceeding +/- 0.5 diopters. Agreement was assessed by a Bland-Altman analyses.<h4>Results</h4>A total of 100 eyes of 50 patients were examined. The overall mean difference of the uncorrected visual acuity measured -0.01 LogMAR (95%LoA:-0.63-0.60). The variability of the differences decreased in the better uncorrected visual acuity subgroup (95%LoA:-0.25-0.55). The overall mean difference in spherical equivalent between the index and reference test exceeded the non-inferiority margin: -0.58D (95%LoA:-4.49-3.33, P = 0.008). The mean differences for myopic and hyperopic subjects were 0.09 diopters (P = 0.675) and -2.06 diopters (P<0.001), respectively. The corrected visual acuities attained with the web-based derived prescription underachieved significantly (0.22±0.32 logMAR vs. -0.01±0.13 LogMAR, P <0.001).<h4>Conclusions</h4>Regarding visual acuity, the web-based tool shows promising results for remotely assessing visual acuity in keratoconus patients, particularly for subjects within a better visual acuity range. This could provide physicians with a quantifiable outcome to enhance teleconsultations, especially relevant when access to health care is limited. Regarding the assessment of the refractive error, the web-based tool was found to be inferior to the manifest refraction in keratoconus patients. This study underlines the importance of validating digital tools and could serve to increase overall safety of the web-based assessments by better identification of outlier cases.Marc B MuijzerJanneau L J ClaessensFrancesco CassanoDaniel A GodefrooijYves F D M PrevooRobert P L WissePublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 8, p e0256087 (2021)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Marc B Muijzer
Janneau L J Claessens
Francesco Cassano
Daniel A Godefrooij
Yves F D M Prevoo
Robert P L Wisse
The evaluation of a web-based tool for measuring the uncorrected visual acuity and refractive error in keratoconus eyes: A method comparison study.
description <h4>Purpose</h4>To evaluate the outcome of a web-based digital assessment of visual acuity and refractive error, compared to a conventional supervised assessment, in keratoconus patients with complex refractive errors.<h4>Material and methods</h4>Keratoconus patients, aged 18 to 40, with a refractive error between -6 and +4 diopters were considered eligible. An uncorrected visual acuity and an assessment of refractive error was taken web-based (index test) and by manifest refraction (reference test) by an optometrist. Corrected visual acuity was assessed with the prescription derived from both the web-based tool and the manifest refraction. Non-inferiority was defined as the 95% limits-of-agreement (95%LoA) of the differences in spherical equivalent between the index and reference test not exceeding +/- 0.5 diopters. Agreement was assessed by a Bland-Altman analyses.<h4>Results</h4>A total of 100 eyes of 50 patients were examined. The overall mean difference of the uncorrected visual acuity measured -0.01 LogMAR (95%LoA:-0.63-0.60). The variability of the differences decreased in the better uncorrected visual acuity subgroup (95%LoA:-0.25-0.55). The overall mean difference in spherical equivalent between the index and reference test exceeded the non-inferiority margin: -0.58D (95%LoA:-4.49-3.33, P = 0.008). The mean differences for myopic and hyperopic subjects were 0.09 diopters (P = 0.675) and -2.06 diopters (P<0.001), respectively. The corrected visual acuities attained with the web-based derived prescription underachieved significantly (0.22±0.32 logMAR vs. -0.01±0.13 LogMAR, P <0.001).<h4>Conclusions</h4>Regarding visual acuity, the web-based tool shows promising results for remotely assessing visual acuity in keratoconus patients, particularly for subjects within a better visual acuity range. This could provide physicians with a quantifiable outcome to enhance teleconsultations, especially relevant when access to health care is limited. Regarding the assessment of the refractive error, the web-based tool was found to be inferior to the manifest refraction in keratoconus patients. This study underlines the importance of validating digital tools and could serve to increase overall safety of the web-based assessments by better identification of outlier cases.
format article
author Marc B Muijzer
Janneau L J Claessens
Francesco Cassano
Daniel A Godefrooij
Yves F D M Prevoo
Robert P L Wisse
author_facet Marc B Muijzer
Janneau L J Claessens
Francesco Cassano
Daniel A Godefrooij
Yves F D M Prevoo
Robert P L Wisse
author_sort Marc B Muijzer
title The evaluation of a web-based tool for measuring the uncorrected visual acuity and refractive error in keratoconus eyes: A method comparison study.
title_short The evaluation of a web-based tool for measuring the uncorrected visual acuity and refractive error in keratoconus eyes: A method comparison study.
title_full The evaluation of a web-based tool for measuring the uncorrected visual acuity and refractive error in keratoconus eyes: A method comparison study.
title_fullStr The evaluation of a web-based tool for measuring the uncorrected visual acuity and refractive error in keratoconus eyes: A method comparison study.
title_full_unstemmed The evaluation of a web-based tool for measuring the uncorrected visual acuity and refractive error in keratoconus eyes: A method comparison study.
title_sort evaluation of a web-based tool for measuring the uncorrected visual acuity and refractive error in keratoconus eyes: a method comparison study.
publisher Public Library of Science (PLoS)
publishDate 2021
url https://doaj.org/article/7adc57127f7e4f72a8012387bf0aae9e
work_keys_str_mv AT marcbmuijzer theevaluationofawebbasedtoolformeasuringtheuncorrectedvisualacuityandrefractiveerrorinkeratoconuseyesamethodcomparisonstudy
AT janneauljclaessens theevaluationofawebbasedtoolformeasuringtheuncorrectedvisualacuityandrefractiveerrorinkeratoconuseyesamethodcomparisonstudy
AT francescocassano theevaluationofawebbasedtoolformeasuringtheuncorrectedvisualacuityandrefractiveerrorinkeratoconuseyesamethodcomparisonstudy
AT danielagodefrooij theevaluationofawebbasedtoolformeasuringtheuncorrectedvisualacuityandrefractiveerrorinkeratoconuseyesamethodcomparisonstudy
AT yvesfdmprevoo theevaluationofawebbasedtoolformeasuringtheuncorrectedvisualacuityandrefractiveerrorinkeratoconuseyesamethodcomparisonstudy
AT robertplwisse theevaluationofawebbasedtoolformeasuringtheuncorrectedvisualacuityandrefractiveerrorinkeratoconuseyesamethodcomparisonstudy
AT marcbmuijzer evaluationofawebbasedtoolformeasuringtheuncorrectedvisualacuityandrefractiveerrorinkeratoconuseyesamethodcomparisonstudy
AT janneauljclaessens evaluationofawebbasedtoolformeasuringtheuncorrectedvisualacuityandrefractiveerrorinkeratoconuseyesamethodcomparisonstudy
AT francescocassano evaluationofawebbasedtoolformeasuringtheuncorrectedvisualacuityandrefractiveerrorinkeratoconuseyesamethodcomparisonstudy
AT danielagodefrooij evaluationofawebbasedtoolformeasuringtheuncorrectedvisualacuityandrefractiveerrorinkeratoconuseyesamethodcomparisonstudy
AT yvesfdmprevoo evaluationofawebbasedtoolformeasuringtheuncorrectedvisualacuityandrefractiveerrorinkeratoconuseyesamethodcomparisonstudy
AT robertplwisse evaluationofawebbasedtoolformeasuringtheuncorrectedvisualacuityandrefractiveerrorinkeratoconuseyesamethodcomparisonstudy
_version_ 1718374352390455296