An ethnically relevant consensus Korean reference genome is a step towards personal reference genomes
The utility of a universal reference sequence for human genome comparisons is dependent on the ethnic origins of the individuals being sequenced. Here the authors report a Korean reference genome and consensus variome, and show that an ethnically-relevant reference can improve variant detection.
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Nature Portfolio
2016
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oai:doaj.org-article:7ade7dd90aad4501a7621d1dc5b2ed0a2021-12-02T14:40:16ZAn ethnically relevant consensus Korean reference genome is a step towards personal reference genomes10.1038/ncomms136372041-1723https://doaj.org/article/7ade7dd90aad4501a7621d1dc5b2ed0a2016-11-01T00:00:00Zhttps://doi.org/10.1038/ncomms13637https://doaj.org/toc/2041-1723The utility of a universal reference sequence for human genome comparisons is dependent on the ethnic origins of the individuals being sequenced. Here the authors report a Korean reference genome and consensus variome, and show that an ethnically-relevant reference can improve variant detection.Yun Sung ChoHyunho KimHak-Min KimSungwoong JhoJeHoon JunYong Joo LeeKyun Shik ChaeChang Geun KimSangsoo KimAnders ErikssonJeremy S. EdwardsSemin LeeByung Chul KimAndrea ManicaTae-Kwang OhGeorge M. ChurchJong BhakNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Yun Sung Cho Hyunho Kim Hak-Min Kim Sungwoong Jho JeHoon Jun Yong Joo Lee Kyun Shik Chae Chang Geun Kim Sangsoo Kim Anders Eriksson Jeremy S. Edwards Semin Lee Byung Chul Kim Andrea Manica Tae-Kwang Oh George M. Church Jong Bhak An ethnically relevant consensus Korean reference genome is a step towards personal reference genomes |
| description |
The utility of a universal reference sequence for human genome comparisons is dependent on the ethnic origins of the individuals being sequenced. Here the authors report a Korean reference genome and consensus variome, and show that an ethnically-relevant reference can improve variant detection. |
| format |
article |
| author |
Yun Sung Cho Hyunho Kim Hak-Min Kim Sungwoong Jho JeHoon Jun Yong Joo Lee Kyun Shik Chae Chang Geun Kim Sangsoo Kim Anders Eriksson Jeremy S. Edwards Semin Lee Byung Chul Kim Andrea Manica Tae-Kwang Oh George M. Church Jong Bhak |
| author_facet |
Yun Sung Cho Hyunho Kim Hak-Min Kim Sungwoong Jho JeHoon Jun Yong Joo Lee Kyun Shik Chae Chang Geun Kim Sangsoo Kim Anders Eriksson Jeremy S. Edwards Semin Lee Byung Chul Kim Andrea Manica Tae-Kwang Oh George M. Church Jong Bhak |
| author_sort |
Yun Sung Cho |
| title |
An ethnically relevant consensus Korean reference genome is a step towards personal reference genomes |
| title_short |
An ethnically relevant consensus Korean reference genome is a step towards personal reference genomes |
| title_full |
An ethnically relevant consensus Korean reference genome is a step towards personal reference genomes |
| title_fullStr |
An ethnically relevant consensus Korean reference genome is a step towards personal reference genomes |
| title_full_unstemmed |
An ethnically relevant consensus Korean reference genome is a step towards personal reference genomes |
| title_sort |
ethnically relevant consensus korean reference genome is a step towards personal reference genomes |
| publisher |
Nature Portfolio |
| publishDate |
2016 |
| url |
https://doaj.org/article/7ade7dd90aad4501a7621d1dc5b2ed0a |
| work_keys_str_mv |
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