High-Resolution Wavefront-Guided Photorefractive Keratectomy and Accelerated Corneal Crosslinking for Stabilization and Visual Rehabilitation of Keratoconus Eyes

High-Resolution Wavefront-Guided Photorefractive Keratectomy and Accelerated Corneal Crosslinking for Stabilization and Visual Rehabilitation of Keratoconus Eyes

Gustavo E Tamayo, Claudia Castell, Pilar Vargas, Eduardo Polania, Juliana Tamayo Bogota Laser Ocular Surgery Center, Bogota, ColombiaCorrespondence: Gustavo E Tamayo Tel +1 305 987 0527Email centrogustavotamayo@gmail.comPurpose: To evaluate the visual and refractive outcomes after high-resolution wa...

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Autores principales: Tamayo GE, Castell C, Vargas P, Polania E, Tamayo J
Formato: article
Lenguaje:EN
Publicado: Dove Medical Press 2020
Materias:
keratoconus management
high resolution wavefront-guided surface ablation with corneal crosslinking
wavefront-guided prk with cxl
visual rehabilitation of keratoconus
Ophthalmology
RE1-994
Acceso en línea:https://doaj.org/article/7ae32d57f55a48c2bb604bd9bd7f441e
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spelling oai:doaj.org-article:7ae32d57f55a48c2bb604bd9bd7f441e2021-12-02T09:43:51ZHigh-Resolution Wavefront-Guided Photorefractive Keratectomy and Accelerated Corneal Crosslinking for Stabilization and Visual Rehabilitation of Keratoconus Eyes1177-5483https://doaj.org/article/7ae32d57f55a48c2bb604bd9bd7f441e2020-05-01T00:00:00Zhttps://www.dovepress.com/high-resolution-wavefront-guided-photorefractive-keratectomy-and-accel-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Gustavo E Tamayo, Claudia Castell, Pilar Vargas, Eduardo Polania, Juliana Tamayo Bogota Laser Ocular Surgery Center, Bogota, ColombiaCorrespondence: Gustavo E Tamayo Tel +1 305 987 0527Email centrogustavotamayo@gmail.comPurpose: To evaluate the visual and refractive outcomes after high-resolution wavefront-guided (HRWG) surface ablation with corneal crosslinking (CXL) in keratoconus eyes.Patients and Methods: In this prospective, interventional case series, 47 eyes of 28 progressive keratoconus patients older than age 18 were enrolled. All patients underwent HRWG photorefractive keratectomy (PRK) with simultaneous accelerated CXL. The study parameters were manifest refraction spherical equivalent (MRSE), keratometric outcomes, uncorrected (UDVA) and corrected distance visual acuity (CDVA) at postoperative 6 and 12 months.Results: There was improvement in mean MRSE from − 2.39± 1.89 D preoperatively to − 0.13 ± 0.68 D at 12 months, with corresponding improvement in UDVA from 0.77 ± 0.35 logMAR to 0.08 ± 0.12 logMAR and CDVA from 0.10 ± 0.11 logMAR to 0.02 ± 0.04 logMAR. Preoperative flat and steep keratometry (K) were 4wct 32.49 ± 1.67 D and 45.94 ± 2.10 D, respectively, and at postoperative 12 months were 41.36 ± 2.08 D and 42.65 ± 2.78 D, respectively. At postoperative 12 months, visual and refractive outcomes were maintained. Comparisons between preoperative and postoperative 12 month timepoints were statistically significant for all parameters.Conclusion: Simultaneous wavefront-guided PRK followed by CXL is a promising treatment for the visual rehabilitation of keratoconus patients.Keywords: keratoconus management, high-resolution wavefront-guided surface ablation with corneal crosslinking, wavefront-guided PRK with CXLTamayo GECastell CVargas PPolania ETamayo JDove Medical Pressarticlekeratoconus managementhigh resolution wavefront-guided surface ablation with corneal crosslinkingwavefront-guided prk with cxlvisual rehabilitation of keratoconusOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 14, Pp 1297-1305 (2020)
institution DOAJ
collection DOAJ
language EN
topic keratoconus management
high resolution wavefront-guided surface ablation with corneal crosslinking
wavefront-guided prk with cxl
visual rehabilitation of keratoconus
Ophthalmology
RE1-994
spellingShingle keratoconus management
high resolution wavefront-guided surface ablation with corneal crosslinking
wavefront-guided prk with cxl
visual rehabilitation of keratoconus
Ophthalmology
RE1-994
Tamayo GE
Castell C
Vargas P
Polania E
Tamayo J
High-Resolution Wavefront-Guided Photorefractive Keratectomy and Accelerated Corneal Crosslinking for Stabilization and Visual Rehabilitation of Keratoconus Eyes
description Gustavo E Tamayo, Claudia Castell, Pilar Vargas, Eduardo Polania, Juliana Tamayo Bogota Laser Ocular Surgery Center, Bogota, ColombiaCorrespondence: Gustavo E Tamayo Tel +1 305 987 0527Email centrogustavotamayo@gmail.comPurpose: To evaluate the visual and refractive outcomes after high-resolution wavefront-guided (HRWG) surface ablation with corneal crosslinking (CXL) in keratoconus eyes.Patients and Methods: In this prospective, interventional case series, 47 eyes of 28 progressive keratoconus patients older than age 18 were enrolled. All patients underwent HRWG photorefractive keratectomy (PRK) with simultaneous accelerated CXL. The study parameters were manifest refraction spherical equivalent (MRSE), keratometric outcomes, uncorrected (UDVA) and corrected distance visual acuity (CDVA) at postoperative 6 and 12 months.Results: There was improvement in mean MRSE from − 2.39± 1.89 D preoperatively to − 0.13 ± 0.68 D at 12 months, with corresponding improvement in UDVA from 0.77 ± 0.35 logMAR to 0.08 ± 0.12 logMAR and CDVA from 0.10 ± 0.11 logMAR to 0.02 ± 0.04 logMAR. Preoperative flat and steep keratometry (K) were 4wct 32.49 ± 1.67 D and 45.94 ± 2.10 D, respectively, and at postoperative 12 months were 41.36 ± 2.08 D and 42.65 ± 2.78 D, respectively. At postoperative 12 months, visual and refractive outcomes were maintained. Comparisons between preoperative and postoperative 12 month timepoints were statistically significant for all parameters.Conclusion: Simultaneous wavefront-guided PRK followed by CXL is a promising treatment for the visual rehabilitation of keratoconus patients.Keywords: keratoconus management, high-resolution wavefront-guided surface ablation with corneal crosslinking, wavefront-guided PRK with CXL
format article
author Tamayo GE
Castell C
Vargas P
Polania E
Tamayo J
author_facet Tamayo GE
Castell C
Vargas P
Polania E
Tamayo J
author_sort Tamayo GE
title High-Resolution Wavefront-Guided Photorefractive Keratectomy and Accelerated Corneal Crosslinking for Stabilization and Visual Rehabilitation of Keratoconus Eyes
title_short High-Resolution Wavefront-Guided Photorefractive Keratectomy and Accelerated Corneal Crosslinking for Stabilization and Visual Rehabilitation of Keratoconus Eyes
title_full High-Resolution Wavefront-Guided Photorefractive Keratectomy and Accelerated Corneal Crosslinking for Stabilization and Visual Rehabilitation of Keratoconus Eyes
title_fullStr High-Resolution Wavefront-Guided Photorefractive Keratectomy and Accelerated Corneal Crosslinking for Stabilization and Visual Rehabilitation of Keratoconus Eyes
title_full_unstemmed High-Resolution Wavefront-Guided Photorefractive Keratectomy and Accelerated Corneal Crosslinking for Stabilization and Visual Rehabilitation of Keratoconus Eyes
title_sort high-resolution wavefront-guided photorefractive keratectomy and accelerated corneal crosslinking for stabilization and visual rehabilitation of keratoconus eyes
publisher Dove Medical Press
publishDate 2020
url https://doaj.org/article/7ae32d57f55a48c2bb604bd9bd7f441e
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AT vargasp highresolutionwavefrontguidedphotorefractivekeratectomyandacceleratedcornealcrosslinkingforstabilizationandvisualrehabilitationofkeratoconuseyes
AT polaniae highresolutionwavefrontguidedphotorefractivekeratectomyandacceleratedcornealcrosslinkingforstabilizationandvisualrehabilitationofkeratoconuseyes
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