Chromatin accessibility maps of chronic lymphocytic leukaemia identify subtype-specific epigenome signatures and transcription regulatory networks

Chronic lymphocytic leukemia (CLL) is characterized by substantial clinical heterogeneity. Here, the authors report the genome-wide chromatin accessibility maps for 88 CLL samples from 55 patients using ATAC-seq, and 10 matched RNA-seq datasets, providing a resource for studying epigenome deregulati...

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Autores principales:	André F. Rendeiro, Christian Schmidl, Jonathan C. Strefford, Renata Walewska, Zadie Davis, Matthias Farlik, David Oscier, Christoph Bock
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/7aeebd444bb84cf4a5f9bc725287aeeb
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spelling	oai:doaj.org-article:7aeebd444bb84cf4a5f9bc725287aeeb2021-12-02T16:58:11ZChromatin accessibility maps of chronic lymphocytic leukaemia identify subtype-specific epigenome signatures and transcription regulatory networks10.1038/ncomms119382041-1723https://doaj.org/article/7aeebd444bb84cf4a5f9bc725287aeeb2016-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms11938https://doaj.org/toc/2041-1723Chronic lymphocytic leukemia (CLL) is characterized by substantial clinical heterogeneity. Here, the authors report the genome-wide chromatin accessibility maps for 88 CLL samples from 55 patients using ATAC-seq, and 10 matched RNA-seq datasets, providing a resource for studying epigenome deregulation in CLL.André F. RendeiroChristian SchmidlJonathan C. StreffordRenata WalewskaZadie DavisMatthias FarlikDavid OscierChristoph BockNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q André F. Rendeiro Christian Schmidl Jonathan C. Strefford Renata Walewska Zadie Davis Matthias Farlik David Oscier Christoph Bock Chromatin accessibility maps of chronic lymphocytic leukaemia identify subtype-specific epigenome signatures and transcription regulatory networks
description	Chronic lymphocytic leukemia (CLL) is characterized by substantial clinical heterogeneity. Here, the authors report the genome-wide chromatin accessibility maps for 88 CLL samples from 55 patients using ATAC-seq, and 10 matched RNA-seq datasets, providing a resource for studying epigenome deregulation in CLL.
format	article
author	André F. Rendeiro Christian Schmidl Jonathan C. Strefford Renata Walewska Zadie Davis Matthias Farlik David Oscier Christoph Bock
author_facet	André F. Rendeiro Christian Schmidl Jonathan C. Strefford Renata Walewska Zadie Davis Matthias Farlik David Oscier Christoph Bock
author_sort	André F. Rendeiro
title	Chromatin accessibility maps of chronic lymphocytic leukaemia identify subtype-specific epigenome signatures and transcription regulatory networks
title_short	Chromatin accessibility maps of chronic lymphocytic leukaemia identify subtype-specific epigenome signatures and transcription regulatory networks
title_full	Chromatin accessibility maps of chronic lymphocytic leukaemia identify subtype-specific epigenome signatures and transcription regulatory networks
title_fullStr	Chromatin accessibility maps of chronic lymphocytic leukaemia identify subtype-specific epigenome signatures and transcription regulatory networks
title_full_unstemmed	Chromatin accessibility maps of chronic lymphocytic leukaemia identify subtype-specific epigenome signatures and transcription regulatory networks
title_sort	chromatin accessibility maps of chronic lymphocytic leukaemia identify subtype-specific epigenome signatures and transcription regulatory networks
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/7aeebd444bb84cf4a5f9bc725287aeeb
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Chromatin accessibility maps of chronic lymphocytic leukaemia identify subtype-specific epigenome signatures and transcription regulatory networks

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