The PGRS Domain of <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> PE_PGRS Protein Rv0297 Is Involved in Endoplasmic Reticulum Stress-Mediated Apoptosis through Toll-Like Receptor 4

The PGRS Domain of <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> PE_PGRS Protein Rv0297 Is Involved in Endoplasmic Reticulum Stress-Mediated Apoptosis through Toll-Like Receptor 4

ABSTRACT The genome of Mycobacterium tuberculosis, the causal organism of tuberculosis (TB), encodes a unique protein family known as the PE/PPE/PGRS family, present exclusively in the genus Mycobacterium and nowhere else in the living kingdom, with largely unexplored functions. We describe the func...

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Detalles Bibliográficos
Autores principales: Sonam Grover, Tarina Sharma, Yadvir Singh, Sakshi Kohli, Manjunath P., Aditi Singh, Torsten Semmler, Lothar H. Wieler, Karsten Tedin, Nasreen Z. Ehtesham, Seyed E. Hasnain
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2018
Materias:
calcium homeostasis
ER localization signal
granulomas
unfolded protein response
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/7aef230cd0a349b8a9528043b29773d0
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