Anticancer activity of oleanolic acid and its derivatives: Recent advances in evidence, target profiling and mechanisms of action
Oleanolic acid (OA, 3 β - hydroxyoleanolic acid-12-en-28-oic acid) is a pentacyclic triterpenoid present in many plants. As a new framework for development of semi synthetic triterpenoids, OA is of great significance in the discovery of anticancer drugs. Some of these derivatives, such as CDDO (2-cy...
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Main Authors: | Zhong-Yuan Tang, Yang Li, Yu-Ting Tang, Xiao-Dong Ma, Ze-Yao Tang |
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Format: | article |
Language: | EN |
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Elsevier
2022
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Online Access: | https://doaj.org/article/7aef5f3ef6ec4b2bac39d66f5a2ffa09 |
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