Development of Anti Acne Cream (w/o/w Multiple Emulsion) Containing Green Tea Leaf Waste

Background: To date, green tea leaf waste is not well utilized, the waste is remain considered as a waste. Previous studies found that green tea leaf waste still have a fairly high EGCG content. EGCG has benefits as an antibacterial. Utilization of green tea leaf waste started from formulation until...

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Autor principal:	Naniek Widyaningrum
Formato:	article
Lenguaje:	EN
Publicado:	Universitas Sultan Agung Semarang 2018
Materias:	multiple emulsion w/o/w green tea leaf residue anti acne p.acnes Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/7af0baa484d442f1b09e8fe47ca27a1e
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spelling	oai:doaj.org-article:7af0baa484d442f1b09e8fe47ca27a1e2021-11-25T13:15:53ZDevelopment of Anti Acne Cream (w/o/w Multiple Emulsion) Containing Green Tea Leaf Waste2085-15452339-093X10.26532/sainsmed.v8i2.2030https://doaj.org/article/7af0baa484d442f1b09e8fe47ca27a1e2018-03-01T00:00:00Zhttp://jurnal.unissula.ac.id/index.php/sainsmedika/article/view/2030https://doaj.org/toc/2085-1545https://doaj.org/toc/2339-093XBackground: To date, green tea leaf waste is not well utilized, the waste is remain considered as a waste. Previous studies found that green tea leaf waste still have a fairly high EGCG content. EGCG has benefits as an antibacterial. Utilization of green tea leaf waste started from formulation until the diversification of multiple emulsion w/o/w products has not been reported. Objective: To develop anti acne cream (W/O/W) multiple emulsion containing green tea leaf waste and evaluate its antibacterial activity against acne-inducing bacteria of Propionibacterium acnes (P.acnes). Methods: Phase one of this research was green tea leaves was extracted by infundation and fractionation method using ethyl acetate and prepared in different concentration (1% to 6%). The second stage was ethyl acetate fraction of green tea leaf extract was tested for its antibacterial activity against P.acnes. Third stage was tested physical properties of formulation with w/o/w multiple emulsion. Results: The optimal antibacterial activity of ethyl acetate fraction of green tea leaf extract against P.acne was at the concentration of 6%, with inhibition zone of 32.6 mm ±0.57. The formula of w/o/w multiple emulsion loaded with green tea leaves waste of 6% active substance demonstrated a good physical properties which can spread 90.4 cm2 ± 0.03, pH 5.00 ± 0.02 and microscopic analysis showed multiple emulsion w/o/w. Conclusion: The concentration of 6% green tea leaf waste formulated in multiple emulsion had a good physical and antibacterial activity for a referred standard. It is necessary to test the stability of multiple emulsion formula.Naniek WidyaningrumUniversitas Sultan Agung Semarangarticlemultiple emulsion w/o/wgreen tea leaf residueanti acnep.acnesMedicine (General)R5-920ENSains Medika, Vol 8, Iss 2 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	multiple emulsion w/o/w green tea leaf residue anti acne p.acnes Medicine (General) R5-920
spellingShingle	multiple emulsion w/o/w green tea leaf residue anti acne p.acnes Medicine (General) R5-920 Naniek Widyaningrum Development of Anti Acne Cream (w/o/w Multiple Emulsion) Containing Green Tea Leaf Waste
description	Background: To date, green tea leaf waste is not well utilized, the waste is remain considered as a waste. Previous studies found that green tea leaf waste still have a fairly high EGCG content. EGCG has benefits as an antibacterial. Utilization of green tea leaf waste started from formulation until the diversification of multiple emulsion w/o/w products has not been reported. Objective: To develop anti acne cream (W/O/W) multiple emulsion containing green tea leaf waste and evaluate its antibacterial activity against acne-inducing bacteria of Propionibacterium acnes (P.acnes). Methods: Phase one of this research was green tea leaves was extracted by infundation and fractionation method using ethyl acetate and prepared in different concentration (1% to 6%). The second stage was ethyl acetate fraction of green tea leaf extract was tested for its antibacterial activity against P.acnes. Third stage was tested physical properties of formulation with w/o/w multiple emulsion. Results: The optimal antibacterial activity of ethyl acetate fraction of green tea leaf extract against P.acne was at the concentration of 6%, with inhibition zone of 32.6 mm ±0.57. The formula of w/o/w multiple emulsion loaded with green tea leaves waste of 6% active substance demonstrated a good physical properties which can spread 90.4 cm2 ± 0.03, pH 5.00 ± 0.02 and microscopic analysis showed multiple emulsion w/o/w. Conclusion: The concentration of 6% green tea leaf waste formulated in multiple emulsion had a good physical and antibacterial activity for a referred standard. It is necessary to test the stability of multiple emulsion formula.
format	article
author	Naniek Widyaningrum
author_facet	Naniek Widyaningrum
author_sort	Naniek Widyaningrum
title	Development of Anti Acne Cream (w/o/w Multiple Emulsion) Containing Green Tea Leaf Waste
title_short	Development of Anti Acne Cream (w/o/w Multiple Emulsion) Containing Green Tea Leaf Waste
title_full	Development of Anti Acne Cream (w/o/w Multiple Emulsion) Containing Green Tea Leaf Waste
title_fullStr	Development of Anti Acne Cream (w/o/w Multiple Emulsion) Containing Green Tea Leaf Waste
title_full_unstemmed	Development of Anti Acne Cream (w/o/w Multiple Emulsion) Containing Green Tea Leaf Waste
title_sort	development of anti acne cream (w/o/w multiple emulsion) containing green tea leaf waste
publisher	Universitas Sultan Agung Semarang
publishDate	2018
url	https://doaj.org/article/7af0baa484d442f1b09e8fe47ca27a1e
work_keys_str_mv	AT naniekwidyaningrum developmentofantiacnecreamwowmultipleemulsioncontaininggreentealeafwaste
_version_	1718413504601391104

Development of Anti Acne Cream (w/o/w Multiple Emulsion) Containing Green Tea Leaf Waste

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