A Generic, Scalable, and Rapid Time-Resolved Förster Resonance Energy Transfer-Based Assay for Antigen Detection—SARS-CoV-2 as a Proof of Concept

PCR is currently the gold standard for the diagnosis of many acute infections. While PCR and its variants are highly sensitive and specific, the time from sampling to results is measured in hours at best.

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Autores principales: Juuso Rusanen, Lauri Kareinen, Leonora Szirovicza, Hasan Uğurlu, Lev Levanov, Anu Jääskeläinen, Maarit Ahava, Satu Kurkela, Kalle Saksela, Klaus Hedman, Olli Vapalahti, Jussi Hepojoki
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Publicado: American Society for Microbiology 2021
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Acceso en línea:https://doaj.org/article/7af21c093fd846b4a1d880d3b2fd06eb
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spelling oai:doaj.org-article:7af21c093fd846b4a1d880d3b2fd06eb2021-11-03T21:15:05ZA Generic, Scalable, and Rapid Time-Resolved Förster Resonance Energy Transfer-Based Assay for Antigen Detection—SARS-CoV-2 as a Proof of Concept2150-751110.1128/mBio.00902-21https://doaj.org/article/7af21c093fd846b4a1d880d3b2fd06eb2021-06-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.00902-21https://doaj.org/toc/2150-7511 PCR is currently the gold standard for the diagnosis of many acute infections. While PCR and its variants are highly sensitive and specific, the time from sampling to results is measured in hours at best.Juuso RusanenLauri KareinenLeonora SziroviczaHasan UğurluLev LevanovAnu JääskeläinenMaarit AhavaSatu KurkelaKalle SakselaKlaus HedmanOlli VapalahtiJussi HepojokiAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 3 (2021)
institution DOAJ
collection DOAJ
language EN
topic Microbiology
QR1-502
spellingShingle Microbiology
QR1-502
Juuso Rusanen
Lauri Kareinen
Leonora Szirovicza
Hasan Uğurlu
Lev Levanov
Anu Jääskeläinen
Maarit Ahava
Satu Kurkela
Kalle Saksela
Klaus Hedman
Olli Vapalahti
Jussi Hepojoki
A Generic, Scalable, and Rapid Time-Resolved Förster Resonance Energy Transfer-Based Assay for Antigen Detection—SARS-CoV-2 as a Proof of Concept
description PCR is currently the gold standard for the diagnosis of many acute infections. While PCR and its variants are highly sensitive and specific, the time from sampling to results is measured in hours at best.
format article
author Juuso Rusanen
Lauri Kareinen
Leonora Szirovicza
Hasan Uğurlu
Lev Levanov
Anu Jääskeläinen
Maarit Ahava
Satu Kurkela
Kalle Saksela
Klaus Hedman
Olli Vapalahti
Jussi Hepojoki
author_facet Juuso Rusanen
Lauri Kareinen
Leonora Szirovicza
Hasan Uğurlu
Lev Levanov
Anu Jääskeläinen
Maarit Ahava
Satu Kurkela
Kalle Saksela
Klaus Hedman
Olli Vapalahti
Jussi Hepojoki
author_sort Juuso Rusanen
title A Generic, Scalable, and Rapid Time-Resolved Förster Resonance Energy Transfer-Based Assay for Antigen Detection—SARS-CoV-2 as a Proof of Concept
title_short A Generic, Scalable, and Rapid Time-Resolved Förster Resonance Energy Transfer-Based Assay for Antigen Detection—SARS-CoV-2 as a Proof of Concept
title_full A Generic, Scalable, and Rapid Time-Resolved Förster Resonance Energy Transfer-Based Assay for Antigen Detection—SARS-CoV-2 as a Proof of Concept
title_fullStr A Generic, Scalable, and Rapid Time-Resolved Förster Resonance Energy Transfer-Based Assay for Antigen Detection—SARS-CoV-2 as a Proof of Concept
title_full_unstemmed A Generic, Scalable, and Rapid Time-Resolved Förster Resonance Energy Transfer-Based Assay for Antigen Detection—SARS-CoV-2 as a Proof of Concept
title_sort generic, scalable, and rapid time-resolved förster resonance energy transfer-based assay for antigen detection—sars-cov-2 as a proof of concept
publisher American Society for Microbiology
publishDate 2021
url https://doaj.org/article/7af21c093fd846b4a1d880d3b2fd06eb
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