Pengaruh Desain Stent pada Jumlah Limfosit dan Trombosit Kelinci (Oryctolagus Cuniculus)

Percutaneous Coronary Intervention (PCI) is an effective treatment for coronary artery diseases. For the procedure, a stent is put in the coronary arteries. There are a variety of stent materials and designs available on the market. The development of stents continues with the goal to reduce the ris...

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Autores principales:	Widowati Siswomihardjo, Dyah Anindya Widyasrini, Dinar Arifianto, Setyo Budhi, Nahar Taufiq
Formato:	article
Lenguaje:	EN ID
Publicado:	Universitas Gadjah Mada 2019
Materias:	stent design lymphocytes platelets inflammation Technology T Technology (General) T1-995 Science Q Science (General) Q1-390
Acceso en línea:	https://doaj.org/article/7b0772b1511c4da7a368a398d1a0345b
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spelling	oai:doaj.org-article:7b0772b1511c4da7a368a398d1a0345b2021-11-14T03:34:21ZPengaruh Desain Stent pada Jumlah Limfosit dan Trombosit Kelinci (Oryctolagus Cuniculus)2089-61312443-131110.22146/teknosains.51526https://doaj.org/article/7b0772b1511c4da7a368a398d1a0345b2019-11-01T00:00:00Zhttps://jurnal.ugm.ac.id/teknosains/article/view/51526https://doaj.org/toc/2089-6131https://doaj.org/toc/2443-1311Percutaneous Coronary Intervention (PCI) is an effective treatment for coronary artery diseases. For the procedure, a stent is put in the coronary arteries. There are a variety of stent materials and designs available on the market. The development of stents continues with the goal to reduce the risk of failure. The design and the ability of the stent as a vascular scaffold are important factors for the success of the stent. The implantation of a stent as a foreign body can lead to inflammation. In general, the inflammation is characterized by an increased number of lymphocytes. Then, platelets play a role in coordinating the occurrence of inflammation and immune response. This study aims to determine the effect of stent design on the number of lymphocytes and platelets as a marker of inflammation. The study was conducted on ten rabbits divided into two treatment groups, namely KP1 (new design stent) and KP2 (commercial stent) by placing a stent on the iliac artery. One hour before stenting, 2 ml of blood was collected in all experimental animals. Then, 2 ml of blood was collected again on the 7th and 28th day after stenting. Data was collected based on the number of lymphocytes and platelets from all experimental animals. Statistical analysis using two-way ANOVA shows no significant difference (p> 0.05) on the number of lymphocytes and platelets between the two groups with different stent designs. It can be concluded that the design of a stent does not show a tendency to cause inflammation.Widowati SiswomihardjoDyah Anindya WidyasriniDinar ArifiantoSetyo BudhiNahar TaufiqUniversitas Gadjah MadaarticlestentdesignlymphocytesplateletsinflammationTechnologyTTechnology (General)T1-995ScienceQScience (General)Q1-390ENIDJurnal Teknosains: Jurnal Ilmiah Sains dan Teknologi, Vol 9, Iss 1, Pp 21-28 (2019)
institution	DOAJ
collection	DOAJ
language	EN ID
topic	stent design lymphocytes platelets inflammation Technology T Technology (General) T1-995 Science Q Science (General) Q1-390
spellingShingle	stent design lymphocytes platelets inflammation Technology T Technology (General) T1-995 Science Q Science (General) Q1-390 Widowati Siswomihardjo Dyah Anindya Widyasrini Dinar Arifianto Setyo Budhi Nahar Taufiq Pengaruh Desain Stent pada Jumlah Limfosit dan Trombosit Kelinci (Oryctolagus Cuniculus)
description	Percutaneous Coronary Intervention (PCI) is an effective treatment for coronary artery diseases. For the procedure, a stent is put in the coronary arteries. There are a variety of stent materials and designs available on the market. The development of stents continues with the goal to reduce the risk of failure. The design and the ability of the stent as a vascular scaffold are important factors for the success of the stent. The implantation of a stent as a foreign body can lead to inflammation. In general, the inflammation is characterized by an increased number of lymphocytes. Then, platelets play a role in coordinating the occurrence of inflammation and immune response. This study aims to determine the effect of stent design on the number of lymphocytes and platelets as a marker of inflammation. The study was conducted on ten rabbits divided into two treatment groups, namely KP1 (new design stent) and KP2 (commercial stent) by placing a stent on the iliac artery. One hour before stenting, 2 ml of blood was collected in all experimental animals. Then, 2 ml of blood was collected again on the 7th and 28th day after stenting. Data was collected based on the number of lymphocytes and platelets from all experimental animals. Statistical analysis using two-way ANOVA shows no significant difference (p> 0.05) on the number of lymphocytes and platelets between the two groups with different stent designs. It can be concluded that the design of a stent does not show a tendency to cause inflammation.
format	article
author	Widowati Siswomihardjo Dyah Anindya Widyasrini Dinar Arifianto Setyo Budhi Nahar Taufiq
author_facet	Widowati Siswomihardjo Dyah Anindya Widyasrini Dinar Arifianto Setyo Budhi Nahar Taufiq
author_sort	Widowati Siswomihardjo
title	Pengaruh Desain Stent pada Jumlah Limfosit dan Trombosit Kelinci (Oryctolagus Cuniculus)
title_short	Pengaruh Desain Stent pada Jumlah Limfosit dan Trombosit Kelinci (Oryctolagus Cuniculus)
title_full	Pengaruh Desain Stent pada Jumlah Limfosit dan Trombosit Kelinci (Oryctolagus Cuniculus)
title_fullStr	Pengaruh Desain Stent pada Jumlah Limfosit dan Trombosit Kelinci (Oryctolagus Cuniculus)
title_full_unstemmed	Pengaruh Desain Stent pada Jumlah Limfosit dan Trombosit Kelinci (Oryctolagus Cuniculus)
title_sort	pengaruh desain stent pada jumlah limfosit dan trombosit kelinci (oryctolagus cuniculus)
publisher	Universitas Gadjah Mada
publishDate	2019
url	https://doaj.org/article/7b0772b1511c4da7a368a398d1a0345b
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Pengaruh Desain Stent pada Jumlah Limfosit dan Trombosit Kelinci (Oryctolagus Cuniculus)

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