Epidemiology of cleft lip and cleft palate in Gorgan, 1998-2003

Background and Objective: Cleft lip and palate is one of the most common human congenital craniofacial abnormalities with the side effects of middle-ear infections, hard of hearing, nutritional problems, speaking, and other societal burdens. The objective of this study was to assess the frequency of...

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Autores principales: MJ Golali Pour, S Mohammadian, MH Taziki, E Mobasheri, A Borghei
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Lenguaje:EN
FA
Publicado: Babol University of Medical Sciences 2005
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spelling oai:doaj.org-article:7b0a737595f546919a0f4c35b411f4a42021-11-10T09:14:32ZEpidemiology of cleft lip and cleft palate in Gorgan, 1998-20031561-41072251-7170https://doaj.org/article/7b0a737595f546919a0f4c35b411f4a42005-04-01T00:00:00Zhttp://jbums.org/article-1-2636-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170Background and Objective: Cleft lip and palate is one of the most common human congenital craniofacial abnormalities with the side effects of middle-ear infections, hard of hearing, nutritional problems, speaking, and other societal burdens. The objective of this study was to assess the frequency of cleft lip and palate and its relation with sex, ethnic group, paternal and maternal age, consanguineous marriage and season in Gorgan during 6 years. Methods: This cross-sectional study was done on 37951 births in Gorgan’s Dezyani hospital during 1998-2003. Sex, type of abnormalities, ethnic group, paternal and maternal age, consanguineous marriage, season and date of birth were recorded in questionnaires and data were analyzed by SPSS. Findings: The prevalence of cleft lip and cleft palate was 0.97 per 1000 birth and it was more common in males (1.08 per 1000) than in females (0.86 per 1000). The rate of cleft was 0.86, 0.89 and 1.47 per 1000 in native Fars, Turkaman and Sistani ethnic group, respectively. 29.7% of parents had consanguineous marriage. 29.7% of mothers with affected newborns consumed different drugs during pregnancy. The commonest rate was in winter and autumn. Maternal and paternal age was 35.5 and 28.5 years, respectively. Cleft was more common in 1998. Conclusion: This study reveals that incidence of cleft in Gorgan is much closer to European and east Asian countries. Consanguineous marriage and the toxicity of pregnant women with drugs or chemicals can induce cleft palate.MJ Golali PourS MohammadianMH TazikiE MobasheriA BorgheiBabol University of Medical Sciencesarticlecleft lipcleft palateepidemiologyethnicitysexMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 7, Iss 2, Pp 41-47 (2005)
institution DOAJ
collection DOAJ
language EN
FA
topic cleft lip
cleft palate
epidemiology
ethnicity
sex
Medicine
R
Medicine (General)
R5-920
spellingShingle cleft lip
cleft palate
epidemiology
ethnicity
sex
Medicine
R
Medicine (General)
R5-920
MJ Golali Pour
S Mohammadian
MH Taziki
E Mobasheri
A Borghei
Epidemiology of cleft lip and cleft palate in Gorgan, 1998-2003
description Background and Objective: Cleft lip and palate is one of the most common human congenital craniofacial abnormalities with the side effects of middle-ear infections, hard of hearing, nutritional problems, speaking, and other societal burdens. The objective of this study was to assess the frequency of cleft lip and palate and its relation with sex, ethnic group, paternal and maternal age, consanguineous marriage and season in Gorgan during 6 years. Methods: This cross-sectional study was done on 37951 births in Gorgan’s Dezyani hospital during 1998-2003. Sex, type of abnormalities, ethnic group, paternal and maternal age, consanguineous marriage, season and date of birth were recorded in questionnaires and data were analyzed by SPSS. Findings: The prevalence of cleft lip and cleft palate was 0.97 per 1000 birth and it was more common in males (1.08 per 1000) than in females (0.86 per 1000). The rate of cleft was 0.86, 0.89 and 1.47 per 1000 in native Fars, Turkaman and Sistani ethnic group, respectively. 29.7% of parents had consanguineous marriage. 29.7% of mothers with affected newborns consumed different drugs during pregnancy. The commonest rate was in winter and autumn. Maternal and paternal age was 35.5 and 28.5 years, respectively. Cleft was more common in 1998. Conclusion: This study reveals that incidence of cleft in Gorgan is much closer to European and east Asian countries. Consanguineous marriage and the toxicity of pregnant women with drugs or chemicals can induce cleft palate.
format article
author MJ Golali Pour
S Mohammadian
MH Taziki
E Mobasheri
A Borghei
author_facet MJ Golali Pour
S Mohammadian
MH Taziki
E Mobasheri
A Borghei
author_sort MJ Golali Pour
title Epidemiology of cleft lip and cleft palate in Gorgan, 1998-2003
title_short Epidemiology of cleft lip and cleft palate in Gorgan, 1998-2003
title_full Epidemiology of cleft lip and cleft palate in Gorgan, 1998-2003
title_fullStr Epidemiology of cleft lip and cleft palate in Gorgan, 1998-2003
title_full_unstemmed Epidemiology of cleft lip and cleft palate in Gorgan, 1998-2003
title_sort epidemiology of cleft lip and cleft palate in gorgan, 1998-2003
publisher Babol University of Medical Sciences
publishDate 2005
url https://doaj.org/article/7b0a737595f546919a0f4c35b411f4a4
work_keys_str_mv AT mjgolalipour epidemiologyofcleftlipandcleftpalateingorgan19982003
AT smohammadian epidemiologyofcleftlipandcleftpalateingorgan19982003
AT mhtaziki epidemiologyofcleftlipandcleftpalateingorgan19982003
AT emobasheri epidemiologyofcleftlipandcleftpalateingorgan19982003
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