Molecular basis of maintaining an oxidizing environment under anaerobiosis by soluble fumarate reductase

Soluble fumarate reductases are essential for eukaryotic cell survival under anaerobic conditions but their mechanism is not fully understood. Here, the authors present structural and enzymatic analyses of yeast fumarate reductase Osm1, elucidating the molecular basis of maintaining redox balance du...

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Autores principales: Sunghwan Kim, Chang Min Kim, Young-Jin Son, Jae Young Choi, Rahel K. Siegenthaler, Younho Lee, Tae-Ho Jang, Jaeyoung Song, Hara Kang, Chris A. Kaiser, Hyun Ho Park
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/7b0bc7c235534d55a3a206a1448ff50f
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Sumario:Soluble fumarate reductases are essential for eukaryotic cell survival under anaerobic conditions but their mechanism is not fully understood. Here, the authors present structural and enzymatic analyses of yeast fumarate reductase Osm1, elucidating the molecular basis of maintaining redox balance during anaerobiosis.