Descemet’s stripping and non-Descemet’s stripping automated endothelial keratoplasty for microcornea using 6.0 mm donor grafts

Descemet’s stripping and non-Descemet’s stripping automated endothelial keratoplasty for microcornea using 6.0 mm donor grafts

Hideaki Yokogawa,1 Akira Kobayashi,1 Natsuko Yamazaki,1 Yoshiki Ueta,2 Yoshihiro Hashimoto,2 Naoko Tachi,2 Kazuhisa Sugiyama11Department of Ophthalmology, Kanazawa University Graduate School of Medical Science, Kanazawa, 2Department of Ophthalmology, Shinseikai Toyama Hospital, Imizu-shi, JapanBackg...

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Autores principales: Yokogawa H, Kobayashi A, Yamazaki N, Ueta Y, Hashimoto Y, Tachi N, Sugiyama K
Formato: article
Lenguaje:EN
Publicado: Dove Medical Press 2013
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Ophthalmology
RE1-994
Acceso en línea:https://doaj.org/article/7b16e6445408494da9187d511af640b3
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spelling oai:doaj.org-article:7b16e6445408494da9187d511af640b32021-12-02T00:31:00ZDescemet’s stripping and non-Descemet’s stripping automated endothelial keratoplasty for microcornea using 6.0 mm donor grafts1177-54671177-5483https://doaj.org/article/7b16e6445408494da9187d511af640b32013-09-01T00:00:00Zhttp://www.dovepress.com/descemetrsquos-stripping-and-non-descemetrsquos-stripping-automated-en-a14516https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Hideaki Yokogawa,1 Akira Kobayashi,1 Natsuko Yamazaki,1 Yoshiki Ueta,2 Yoshihiro Hashimoto,2 Naoko Tachi,2 Kazuhisa Sugiyama11Department of Ophthalmology, Kanazawa University Graduate School of Medical Science, Kanazawa, 2Department of Ophthalmology, Shinseikai Toyama Hospital, Imizu-shi, JapanBackground: The purpose of this paper is to report our experience of Descemet’s stripping and non-Descemet’s stripping automated endothelial keratoplasty (DSAEK/nDSAEK) for microcorneas using 6.0 mm donor grafts.Methods: Three eyes of two patients (a 56-year-old woman and a 59-year-old woman) with microcornea and suffering from bullous keratopathy were treated with either DSAEK or nDSAEK. A small donor graft (6.0 mm) was inserted into the anterior chamber using a double glide (Busin glide and intraocular lens sheet glide) donor insertion technique. Both patients were followed for at least 12 months. Clinical outcomes, including intraoperative and postoperative complications, visual acuity, and endothelial cell density were evaluated.Results: In all three cases (100%), no intraoperative complications were noted. In one case with a flat keratometry value (32.13 D), a partial donor detachment was noted one day postoperatively, but it was reattached by rebubbling. In another case, rejection was noted 8 months postoperatively, but treatment with systemic corticosteroids was successful. A clear cornea remained in all three cases (100%), with best-corrected visual acuity greater than 20/100 (mean 20/50) at 12 months. Mean postoperative endothelial cell counts were 2,603 ± 18 cells/mm2 at 6 months (7.4% decrease from preoperative donor cell counts) and 1,799 ± 556 cells/mm2 at 12 months (36.5% decrease).Conclusion: We report for the first time the successful use of a small donor graft (6.0 mm) for DSAEK/nDSAEK in cases of microcornea. Additional studies using a large number of patients are required to evaluate fully the potential advantages and drawbacks of small diameter donor grafts for microcornea.Keywords: microcornea, Descemet’s stripping, non-Descemet’s stripping, automated endothelial keratoplasty, small donor graftsYokogawa HKobayashi AYamazaki NUeta YHashimoto YTachi NSugiyama KDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2013, Iss default, Pp 1951-1956 (2013)
institution DOAJ
collection DOAJ
language EN
topic Ophthalmology
RE1-994
spellingShingle Ophthalmology
RE1-994
Yokogawa H
Kobayashi A
Yamazaki N
Ueta Y
Hashimoto Y
Tachi N
Sugiyama K
Descemet’s stripping and non-Descemet’s stripping automated endothelial keratoplasty for microcornea using 6.0 mm donor grafts
description Hideaki Yokogawa,1 Akira Kobayashi,1 Natsuko Yamazaki,1 Yoshiki Ueta,2 Yoshihiro Hashimoto,2 Naoko Tachi,2 Kazuhisa Sugiyama11Department of Ophthalmology, Kanazawa University Graduate School of Medical Science, Kanazawa, 2Department of Ophthalmology, Shinseikai Toyama Hospital, Imizu-shi, JapanBackground: The purpose of this paper is to report our experience of Descemet’s stripping and non-Descemet’s stripping automated endothelial keratoplasty (DSAEK/nDSAEK) for microcorneas using 6.0 mm donor grafts.Methods: Three eyes of two patients (a 56-year-old woman and a 59-year-old woman) with microcornea and suffering from bullous keratopathy were treated with either DSAEK or nDSAEK. A small donor graft (6.0 mm) was inserted into the anterior chamber using a double glide (Busin glide and intraocular lens sheet glide) donor insertion technique. Both patients were followed for at least 12 months. Clinical outcomes, including intraoperative and postoperative complications, visual acuity, and endothelial cell density were evaluated.Results: In all three cases (100%), no intraoperative complications were noted. In one case with a flat keratometry value (32.13 D), a partial donor detachment was noted one day postoperatively, but it was reattached by rebubbling. In another case, rejection was noted 8 months postoperatively, but treatment with systemic corticosteroids was successful. A clear cornea remained in all three cases (100%), with best-corrected visual acuity greater than 20/100 (mean 20/50) at 12 months. Mean postoperative endothelial cell counts were 2,603 ± 18 cells/mm2 at 6 months (7.4% decrease from preoperative donor cell counts) and 1,799 ± 556 cells/mm2 at 12 months (36.5% decrease).Conclusion: We report for the first time the successful use of a small donor graft (6.0 mm) for DSAEK/nDSAEK in cases of microcornea. Additional studies using a large number of patients are required to evaluate fully the potential advantages and drawbacks of small diameter donor grafts for microcornea.Keywords: microcornea, Descemet’s stripping, non-Descemet’s stripping, automated endothelial keratoplasty, small donor grafts
format article
author Yokogawa H
Kobayashi A
Yamazaki N
Ueta Y
Hashimoto Y
Tachi N
Sugiyama K
author_facet Yokogawa H
Kobayashi A
Yamazaki N
Ueta Y
Hashimoto Y
Tachi N
Sugiyama K
author_sort Yokogawa H
title Descemet’s stripping and non-Descemet’s stripping automated endothelial keratoplasty for microcornea using 6.0 mm donor grafts
title_short Descemet’s stripping and non-Descemet’s stripping automated endothelial keratoplasty for microcornea using 6.0 mm donor grafts
title_full Descemet’s stripping and non-Descemet’s stripping automated endothelial keratoplasty for microcornea using 6.0 mm donor grafts
title_fullStr Descemet’s stripping and non-Descemet’s stripping automated endothelial keratoplasty for microcornea using 6.0 mm donor grafts
title_full_unstemmed Descemet’s stripping and non-Descemet’s stripping automated endothelial keratoplasty for microcornea using 6.0 mm donor grafts
title_sort descemet’s stripping and non-descemet’s stripping automated endothelial keratoplasty for microcornea using 6.0 mm donor grafts
publisher Dove Medical Press
publishDate 2013
url https://doaj.org/article/7b16e6445408494da9187d511af640b3
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