Meibomian Gland Morphology Changes After Cataract Surgery: A Contra-Lateral Eye Study

Purpose: To evaluate the morphology changes of meibomian glands (MGs) after cataract surgery.Setting: Hangzhou Branch of the Eye Hospital of Wenzhou Medical University, Zhejiang, China.Methods: In this contra-lateral eye study, 40 patients received unilateral cataract surgery for age-related catarac...

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Autores principales:	Pingjun Chang, Shuyi Qian, Zhizi Xu, Feng Huang, Yinying Zhao, Zhangliang Li, Yun-e Zhao
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	meibomian gland morphology meibomian gland dysfunction dry eye disease meibomian gland atrophy cataract surgery self-contrast study Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/7b1bcbb87fd74b33822e087d103879cc
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spelling	oai:doaj.org-article:7b1bcbb87fd74b33822e087d103879cc2021-12-01T13:14:16ZMeibomian Gland Morphology Changes After Cataract Surgery: A Contra-Lateral Eye Study2296-858X10.3389/fmed.2021.766393https://doaj.org/article/7b1bcbb87fd74b33822e087d103879cc2021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fmed.2021.766393/fullhttps://doaj.org/toc/2296-858XPurpose: To evaluate the morphology changes of meibomian glands (MGs) after cataract surgery.Setting: Hangzhou Branch of the Eye Hospital of Wenzhou Medical University, Zhejiang, China.Methods: In this contra-lateral eye study, 40 patients received unilateral cataract surgery for age-related cataract. All the patients underwent the evaluation of non-invasive break-up time (NIBUT) and lower tear meniscus height (TMH) before the surgery and 6 months post-operatively. The MGs were evaluated via ImageJ and Meibomian Gland Bio-image Analyzer. MG dropout, length, width, area, gland diameter deformation index (DI), and gland signal index (SI) were recorded.Results: MG length, width, area, DI, and SI were significantly decreased after cataract surgery in the study group (operated eyes, P < 0.001, P = 0.003, P < 0.001, P = 0.001, and P < 0.001, respectively) and showed no significant changes in the control group (non-operated eyes) (all P > 0.05). MG loss increased more in the study group (P = 0.030), and the changes in TMH and NIBUT were not significantly different between the two eyes (both P > 0.05).Conclusion: Cataract surgery aggravated meibomian gland morphology, such as MG loss, MG length, width, area, and SI, and produced no change in NIBUT and TMH at 6 months post-operatively.Pingjun ChangPingjun ChangPingjun ChangShuyi QianShuyi QianShuyi QianZhizi XuFeng HuangFeng HuangFeng HuangYinying ZhaoYinying ZhaoYinying ZhaoZhangliang LiZhangliang LiZhangliang LiYun-e ZhaoYun-e ZhaoYun-e ZhaoFrontiers Media S.A.articlemeibomian gland morphologymeibomian gland dysfunctiondry eye diseasemeibomian gland atrophycataract surgeryself-contrast studyMedicine (General)R5-920ENFrontiers in Medicine, Vol 8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	meibomian gland morphology meibomian gland dysfunction dry eye disease meibomian gland atrophy cataract surgery self-contrast study Medicine (General) R5-920
spellingShingle	meibomian gland morphology meibomian gland dysfunction dry eye disease meibomian gland atrophy cataract surgery self-contrast study Medicine (General) R5-920 Pingjun Chang Pingjun Chang Pingjun Chang Shuyi Qian Shuyi Qian Shuyi Qian Zhizi Xu Feng Huang Feng Huang Feng Huang Yinying Zhao Yinying Zhao Yinying Zhao Zhangliang Li Zhangliang Li Zhangliang Li Yun-e Zhao Yun-e Zhao Yun-e Zhao Meibomian Gland Morphology Changes After Cataract Surgery: A Contra-Lateral Eye Study
description	Purpose: To evaluate the morphology changes of meibomian glands (MGs) after cataract surgery.Setting: Hangzhou Branch of the Eye Hospital of Wenzhou Medical University, Zhejiang, China.Methods: In this contra-lateral eye study, 40 patients received unilateral cataract surgery for age-related cataract. All the patients underwent the evaluation of non-invasive break-up time (NIBUT) and lower tear meniscus height (TMH) before the surgery and 6 months post-operatively. The MGs were evaluated via ImageJ and Meibomian Gland Bio-image Analyzer. MG dropout, length, width, area, gland diameter deformation index (DI), and gland signal index (SI) were recorded.Results: MG length, width, area, DI, and SI were significantly decreased after cataract surgery in the study group (operated eyes, P < 0.001, P = 0.003, P < 0.001, P = 0.001, and P < 0.001, respectively) and showed no significant changes in the control group (non-operated eyes) (all P > 0.05). MG loss increased more in the study group (P = 0.030), and the changes in TMH and NIBUT were not significantly different between the two eyes (both P > 0.05).Conclusion: Cataract surgery aggravated meibomian gland morphology, such as MG loss, MG length, width, area, and SI, and produced no change in NIBUT and TMH at 6 months post-operatively.
format	article
author	Pingjun Chang Pingjun Chang Pingjun Chang Shuyi Qian Shuyi Qian Shuyi Qian Zhizi Xu Feng Huang Feng Huang Feng Huang Yinying Zhao Yinying Zhao Yinying Zhao Zhangliang Li Zhangliang Li Zhangliang Li Yun-e Zhao Yun-e Zhao Yun-e Zhao
author_facet	Pingjun Chang Pingjun Chang Pingjun Chang Shuyi Qian Shuyi Qian Shuyi Qian Zhizi Xu Feng Huang Feng Huang Feng Huang Yinying Zhao Yinying Zhao Yinying Zhao Zhangliang Li Zhangliang Li Zhangliang Li Yun-e Zhao Yun-e Zhao Yun-e Zhao
author_sort	Pingjun Chang
title	Meibomian Gland Morphology Changes After Cataract Surgery: A Contra-Lateral Eye Study
title_short	Meibomian Gland Morphology Changes After Cataract Surgery: A Contra-Lateral Eye Study
title_full	Meibomian Gland Morphology Changes After Cataract Surgery: A Contra-Lateral Eye Study
title_fullStr	Meibomian Gland Morphology Changes After Cataract Surgery: A Contra-Lateral Eye Study
title_full_unstemmed	Meibomian Gland Morphology Changes After Cataract Surgery: A Contra-Lateral Eye Study
title_sort	meibomian gland morphology changes after cataract surgery: a contra-lateral eye study
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/7b1bcbb87fd74b33822e087d103879cc
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Meibomian Gland Morphology Changes After Cataract Surgery: A Contra-Lateral Eye Study

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