Cognitive decline tracks motor progression and not disease duration in Parkinson patients

BD Riggeal1, GP Crucian1, P Seignourel2, CE Jacobson IV1, MS Okun1, RL Rodriguez1, Hubert H Fernandez11Department of Neurology; 2Department of Community Health and Psychology, University of Florida, Gainesville, FL, USAAbstract: We performed an analysis of prospectively-acquired cross sectional data...

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Auteurs principaux:	BD Riggeal, GP Crucian, P Seignourel, CE Jacobson IV, MS Okun, et al
Format:	article
Langue:	EN
Publié:	Dove Medical Press 2007
Sujets:	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Accès en ligne:	https://doaj.org/article/7b1c2eea6bb44ec6a62701fbb9c4a2da
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spelling	oai:doaj.org-article:7b1c2eea6bb44ec6a62701fbb9c4a2da2021-12-02T01:35:25ZCognitive decline tracks motor progression and not disease duration in Parkinson patients1176-63281178-2021https://doaj.org/article/7b1c2eea6bb44ec6a62701fbb9c4a2da2007-01-01T00:00:00Zhttp://www.dovepress.com/cognitive-decline-tracks-motor-progression-and-not-disease-duration-in-a976https://doaj.org/toc/1176-6328https://doaj.org/toc/1178-2021BD Riggeal1, GP Crucian1, P Seignourel2, CE Jacobson IV1, MS Okun1, RL Rodriguez1, Hubert H Fernandez11Department of Neurology; 2Department of Community Health and Psychology, University of Florida, Gainesville, FL, USAAbstract: We performed an analysis of prospectively-acquired cross sectional data on 106 Parkinson disease (PD) patients who underwent comprehensive neuropsychological testing and the Unified Parkinson Disease Rating Scale (UPDRS) motor scale. A significant correlation between the UPDRS motor and neuropsychological tests in all cognitive domains except for general intelligence and visuo-spatial function was seen. In this study, cognitive decline within this PD cohort correlated with motor impairment but not disease duration. Our findings suggest that overall cognitive impairment (except visuospatial dysfunction) may track motor progression in PD more than duration of disease. Longitudinal studies are needed to confirm our results.Keywords: Parkinson, dementia, cognition, visual-spatial dysfunction BD RiggealGP CrucianP SeignourelCE Jacobson IVMS Okunet alDove Medical PressarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2007, Iss Issue 6, Pp 955-958 (2007)
institution	DOAJ
collection	DOAJ
language	EN
topic	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 BD Riggeal GP Crucian P Seignourel CE Jacobson IV MS Okun et al Cognitive decline tracks motor progression and not disease duration in Parkinson patients
description	BD Riggeal1, GP Crucian1, P Seignourel2, CE Jacobson IV1, MS Okun1, RL Rodriguez1, Hubert H Fernandez11Department of Neurology; 2Department of Community Health and Psychology, University of Florida, Gainesville, FL, USAAbstract: We performed an analysis of prospectively-acquired cross sectional data on 106 Parkinson disease (PD) patients who underwent comprehensive neuropsychological testing and the Unified Parkinson Disease Rating Scale (UPDRS) motor scale. A significant correlation between the UPDRS motor and neuropsychological tests in all cognitive domains except for general intelligence and visuo-spatial function was seen. In this study, cognitive decline within this PD cohort correlated with motor impairment but not disease duration. Our findings suggest that overall cognitive impairment (except visuospatial dysfunction) may track motor progression in PD more than duration of disease. Longitudinal studies are needed to confirm our results.Keywords: Parkinson, dementia, cognition, visual-spatial dysfunction
format	article
author	BD Riggeal GP Crucian P Seignourel CE Jacobson IV MS Okun et al
author_facet	BD Riggeal GP Crucian P Seignourel CE Jacobson IV MS Okun et al
author_sort	BD Riggeal
title	Cognitive decline tracks motor progression and not disease duration in Parkinson patients
title_short	Cognitive decline tracks motor progression and not disease duration in Parkinson patients
title_full	Cognitive decline tracks motor progression and not disease duration in Parkinson patients
title_fullStr	Cognitive decline tracks motor progression and not disease duration in Parkinson patients
title_full_unstemmed	Cognitive decline tracks motor progression and not disease duration in Parkinson patients
title_sort	cognitive decline tracks motor progression and not disease duration in parkinson patients
publisher	Dove Medical Press
publishDate	2007
url	https://doaj.org/article/7b1c2eea6bb44ec6a62701fbb9c4a2da
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_version_	1718402968207753216

Cognitive decline tracks motor progression and not disease duration in Parkinson patients

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