Developmental kinetics and transcriptome dynamics of stem cell specification in the spermatogenic lineage

In neonatal testes, prospermatogonia generate both spermatogonia for the first wave of spermatogenesis and spermatogonial stem cells (SSCs) for maintenance of spermatogenesis in males. Here the authors characterize the development of mouse SSCs from prospermatogonia using single-cell RNA-seq and tra...

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Autores principales:	Nathan C. Law, Melissa J. Oatley, Jon M. Oatley
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/7b201cffb71c408b8f090a17091456dc
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spelling	oai:doaj.org-article:7b201cffb71c408b8f090a17091456dc2021-12-02T17:33:12ZDevelopmental kinetics and transcriptome dynamics of stem cell specification in the spermatogenic lineage10.1038/s41467-019-10596-02041-1723https://doaj.org/article/7b201cffb71c408b8f090a17091456dc2019-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10596-0https://doaj.org/toc/2041-1723In neonatal testes, prospermatogonia generate both spermatogonia for the first wave of spermatogenesis and spermatogonial stem cells (SSCs) for maintenance of spermatogenesis in males. Here the authors characterize the development of mouse SSCs from prospermatogonia using single-cell RNA-seq and transplantation assays.Nathan C. LawMelissa J. OatleyJon M. OatleyNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Nathan C. Law Melissa J. Oatley Jon M. Oatley Developmental kinetics and transcriptome dynamics of stem cell specification in the spermatogenic lineage
description	In neonatal testes, prospermatogonia generate both spermatogonia for the first wave of spermatogenesis and spermatogonial stem cells (SSCs) for maintenance of spermatogenesis in males. Here the authors characterize the development of mouse SSCs from prospermatogonia using single-cell RNA-seq and transplantation assays.
format	article
author	Nathan C. Law Melissa J. Oatley Jon M. Oatley
author_facet	Nathan C. Law Melissa J. Oatley Jon M. Oatley
author_sort	Nathan C. Law
title	Developmental kinetics and transcriptome dynamics of stem cell specification in the spermatogenic lineage
title_short	Developmental kinetics and transcriptome dynamics of stem cell specification in the spermatogenic lineage
title_full	Developmental kinetics and transcriptome dynamics of stem cell specification in the spermatogenic lineage
title_fullStr	Developmental kinetics and transcriptome dynamics of stem cell specification in the spermatogenic lineage
title_full_unstemmed	Developmental kinetics and transcriptome dynamics of stem cell specification in the spermatogenic lineage
title_sort	developmental kinetics and transcriptome dynamics of stem cell specification in the spermatogenic lineage
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/7b201cffb71c408b8f090a17091456dc
work_keys_str_mv	AT nathanclaw developmentalkineticsandtranscriptomedynamicsofstemcellspecificationinthespermatogeniclineage AT melissajoatley developmentalkineticsandtranscriptomedynamicsofstemcellspecificationinthespermatogeniclineage AT jonmoatley developmentalkineticsandtranscriptomedynamicsofstemcellspecificationinthespermatogeniclineage
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Developmental kinetics and transcriptome dynamics of stem cell specification in the spermatogenic lineage

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