An L-threonine transaldolase is required for L-threo-β-hydroxy-α-amino acid assembly during obafluorin biosynthesis

Obafluorin is a β-lactone antibiotic produced byPseudomonas fluorescens. Here the authors present the biosynthetic gene cluster and biosynthetic pathway of obafluorin, which is characterized by a central transaldolase step catalysed by a rare L-threonine transaldolase.

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Autores principales:	Thomas A. Scott, Daniel Heine, Zhiwei Qin, Barrie Wilkinson
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/7b242d2ca4034e769a1c3a08715872de
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id	oai:doaj.org-article:7b242d2ca4034e769a1c3a08715872de
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spelling	oai:doaj.org-article:7b242d2ca4034e769a1c3a08715872de2021-12-02T14:40:34ZAn L-threonine transaldolase is required for L-threo-β-hydroxy-α-amino acid assembly during obafluorin biosynthesis10.1038/ncomms159352041-1723https://doaj.org/article/7b242d2ca4034e769a1c3a08715872de2017-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms15935https://doaj.org/toc/2041-1723Obafluorin is a β-lactone antibiotic produced byPseudomonas fluorescens. Here the authors present the biosynthetic gene cluster and biosynthetic pathway of obafluorin, which is characterized by a central transaldolase step catalysed by a rare L-threonine transaldolase.Thomas A. ScottDaniel HeineZhiwei QinBarrie WilkinsonNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Thomas A. Scott Daniel Heine Zhiwei Qin Barrie Wilkinson An L-threonine transaldolase is required for L-threo-β-hydroxy-α-amino acid assembly during obafluorin biosynthesis
description	Obafluorin is a β-lactone antibiotic produced byPseudomonas fluorescens. Here the authors present the biosynthetic gene cluster and biosynthetic pathway of obafluorin, which is characterized by a central transaldolase step catalysed by a rare L-threonine transaldolase.
format	article
author	Thomas A. Scott Daniel Heine Zhiwei Qin Barrie Wilkinson
author_facet	Thomas A. Scott Daniel Heine Zhiwei Qin Barrie Wilkinson
author_sort	Thomas A. Scott
title	An L-threonine transaldolase is required for L-threo-β-hydroxy-α-amino acid assembly during obafluorin biosynthesis
title_short	An L-threonine transaldolase is required for L-threo-β-hydroxy-α-amino acid assembly during obafluorin biosynthesis
title_full	An L-threonine transaldolase is required for L-threo-β-hydroxy-α-amino acid assembly during obafluorin biosynthesis
title_fullStr	An L-threonine transaldolase is required for L-threo-β-hydroxy-α-amino acid assembly during obafluorin biosynthesis
title_full_unstemmed	An L-threonine transaldolase is required for L-threo-β-hydroxy-α-amino acid assembly during obafluorin biosynthesis
title_sort	l-threonine transaldolase is required for l-threo-β-hydroxy-α-amino acid assembly during obafluorin biosynthesis
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/7b242d2ca4034e769a1c3a08715872de
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An L-threonine transaldolase is required for L-threo-β-hydroxy-α-amino acid assembly during obafluorin biosynthesis

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