Activation of basal forebrain purinergic P2 receptors promotes wakefulness in mice

Abstract The functions of purinergic P2 receptors (P2Rs) for extracellular adenosine triphosphate (ATP) are poorly understood. Here, for the first time, we show that activation of P2Rs in an important arousal region, the basal forebrain (BF), promotes wakefulness, whereas inhibition of P2Rs promotes...

Full description

Saved in:
Bibliographic Details
Main Authors: Chun Yang, Andrei Larin, James T. McKenna, Kenneth A. Jacobson, Stuart Winston, Robert E. Strecker, Anna Kalinchuk, Radhika Basheer, Ritchie E. Brown
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
R
Q
Online Access:https://doaj.org/article/7b3e1e1e253041a2bc951220bd9dc89a
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items