Regulated membrane remodeling by Mic60 controls formation of mitochondrial crista junctions

The MICOS complex has an essential role in crista junction formation and mitochondrial inner membrane morphology. Here, the authors show that one of its components, Mic60, known to form contact sites between inner and outer membranes, also displays membrane-shaping activity.

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Autores principales:	Manuel Hessenberger, Ralf M. Zerbes, Heike Rampelt, Séverine Kunz, Audrey H. Xavier, Bettina Purfürst, Hauke Lilie, Nikolaus Pfanner, Martin van der Laan, Oliver Daumke
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/7b4425f4e601401a96034bbaf18029f4
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spelling	oai:doaj.org-article:7b4425f4e601401a96034bbaf18029f42021-12-02T14:42:00ZRegulated membrane remodeling by Mic60 controls formation of mitochondrial crista junctions10.1038/ncomms152582041-1723https://doaj.org/article/7b4425f4e601401a96034bbaf18029f42017-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms15258https://doaj.org/toc/2041-1723The MICOS complex has an essential role in crista junction formation and mitochondrial inner membrane morphology. Here, the authors show that one of its components, Mic60, known to form contact sites between inner and outer membranes, also displays membrane-shaping activity.Manuel HessenbergerRalf M. ZerbesHeike RampeltSéverine KunzAudrey H. XavierBettina PurfürstHauke LilieNikolaus PfannerMartin van der LaanOliver DaumkeNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Manuel Hessenberger Ralf M. Zerbes Heike Rampelt Séverine Kunz Audrey H. Xavier Bettina Purfürst Hauke Lilie Nikolaus Pfanner Martin van der Laan Oliver Daumke Regulated membrane remodeling by Mic60 controls formation of mitochondrial crista junctions
description	The MICOS complex has an essential role in crista junction formation and mitochondrial inner membrane morphology. Here, the authors show that one of its components, Mic60, known to form contact sites between inner and outer membranes, also displays membrane-shaping activity.
format	article
author	Manuel Hessenberger Ralf M. Zerbes Heike Rampelt Séverine Kunz Audrey H. Xavier Bettina Purfürst Hauke Lilie Nikolaus Pfanner Martin van der Laan Oliver Daumke
author_facet	Manuel Hessenberger Ralf M. Zerbes Heike Rampelt Séverine Kunz Audrey H. Xavier Bettina Purfürst Hauke Lilie Nikolaus Pfanner Martin van der Laan Oliver Daumke
author_sort	Manuel Hessenberger
title	Regulated membrane remodeling by Mic60 controls formation of mitochondrial crista junctions
title_short	Regulated membrane remodeling by Mic60 controls formation of mitochondrial crista junctions
title_full	Regulated membrane remodeling by Mic60 controls formation of mitochondrial crista junctions
title_fullStr	Regulated membrane remodeling by Mic60 controls formation of mitochondrial crista junctions
title_full_unstemmed	Regulated membrane remodeling by Mic60 controls formation of mitochondrial crista junctions
title_sort	regulated membrane remodeling by mic60 controls formation of mitochondrial crista junctions
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/7b4425f4e601401a96034bbaf18029f4
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Regulated membrane remodeling by Mic60 controls formation of mitochondrial crista junctions

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