Cytoplasmic CPSF6 Regulates HIV-1 Capsid Trafficking and Infection in a Cyclophilin A-Dependent Manner

HIV is the causative agent of AIDS, which has no cure. The protein shell that encases the viral genome, the capsid, is critical for HIV replication in cells at multiple steps.

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Zhou Zhong, Jiying Ning, Emerson A. Boggs, Sooin Jang, Callen Wallace, Cheryl Telmer, Marcel P. Bruchez, Jinwoo Ahn, Alan N. Engelman, Peijun Zhang, Simon C. Watkins, Zandrea Ambrose
Format: article
Langue:EN
Publié: American Society for Microbiology 2021
Sujets:
Accès en ligne:https://doaj.org/article/7b45f007fb61477e9bb4e09bfd2fad63
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
Description
Résumé:HIV is the causative agent of AIDS, which has no cure. The protein shell that encases the viral genome, the capsid, is critical for HIV replication in cells at multiple steps.