Cytoplasmic CPSF6 Regulates HIV-1 Capsid Trafficking and Infection in a Cyclophilin A-Dependent Manner

HIV is the causative agent of AIDS, which has no cure. The protein shell that encases the viral genome, the capsid, is critical for HIV replication in cells at multiple steps.

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Autores principales: Zhou Zhong, Jiying Ning, Emerson A. Boggs, Sooin Jang, Callen Wallace, Cheryl Telmer, Marcel P. Bruchez, Jinwoo Ahn, Alan N. Engelman, Peijun Zhang, Simon C. Watkins, Zandrea Ambrose
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Publicado: American Society for Microbiology 2021
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Acceso en línea:https://doaj.org/article/7b45f007fb61477e9bb4e09bfd2fad63
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spelling oai:doaj.org-article:7b45f007fb61477e9bb4e09bfd2fad632021-11-03T18:56:10ZCytoplasmic CPSF6 Regulates HIV-1 Capsid Trafficking and Infection in a Cyclophilin A-Dependent Manner2150-751110.1128/mBio.03142-20https://doaj.org/article/7b45f007fb61477e9bb4e09bfd2fad632021-04-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.03142-20https://doaj.org/toc/2150-7511 HIV is the causative agent of AIDS, which has no cure. The protein shell that encases the viral genome, the capsid, is critical for HIV replication in cells at multiple steps.Zhou ZhongJiying NingEmerson A. BoggsSooin JangCallen WallaceCheryl TelmerMarcel P. BruchezJinwoo AhnAlan N. EngelmanPeijun ZhangSimon C. WatkinsZandrea AmbroseAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 2 (2021)
institution DOAJ
collection DOAJ
language EN
topic Microbiology
QR1-502
spellingShingle Microbiology
QR1-502
Zhou Zhong
Jiying Ning
Emerson A. Boggs
Sooin Jang
Callen Wallace
Cheryl Telmer
Marcel P. Bruchez
Jinwoo Ahn
Alan N. Engelman
Peijun Zhang
Simon C. Watkins
Zandrea Ambrose
Cytoplasmic CPSF6 Regulates HIV-1 Capsid Trafficking and Infection in a Cyclophilin A-Dependent Manner
description HIV is the causative agent of AIDS, which has no cure. The protein shell that encases the viral genome, the capsid, is critical for HIV replication in cells at multiple steps.
format article
author Zhou Zhong
Jiying Ning
Emerson A. Boggs
Sooin Jang
Callen Wallace
Cheryl Telmer
Marcel P. Bruchez
Jinwoo Ahn
Alan N. Engelman
Peijun Zhang
Simon C. Watkins
Zandrea Ambrose
author_facet Zhou Zhong
Jiying Ning
Emerson A. Boggs
Sooin Jang
Callen Wallace
Cheryl Telmer
Marcel P. Bruchez
Jinwoo Ahn
Alan N. Engelman
Peijun Zhang
Simon C. Watkins
Zandrea Ambrose
author_sort Zhou Zhong
title Cytoplasmic CPSF6 Regulates HIV-1 Capsid Trafficking and Infection in a Cyclophilin A-Dependent Manner
title_short Cytoplasmic CPSF6 Regulates HIV-1 Capsid Trafficking and Infection in a Cyclophilin A-Dependent Manner
title_full Cytoplasmic CPSF6 Regulates HIV-1 Capsid Trafficking and Infection in a Cyclophilin A-Dependent Manner
title_fullStr Cytoplasmic CPSF6 Regulates HIV-1 Capsid Trafficking and Infection in a Cyclophilin A-Dependent Manner
title_full_unstemmed Cytoplasmic CPSF6 Regulates HIV-1 Capsid Trafficking and Infection in a Cyclophilin A-Dependent Manner
title_sort cytoplasmic cpsf6 regulates hiv-1 capsid trafficking and infection in a cyclophilin a-dependent manner
publisher American Society for Microbiology
publishDate 2021
url https://doaj.org/article/7b45f007fb61477e9bb4e09bfd2fad63
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