Roles for DNA polymerase δ in initiating and terminating leading strand DNA replication
DNA polymerases epsilon and delta, respectively, perform the majority of leading and lagging strand replication of the eukaryotic nuclear genome. Here the authors map the ribonucleotide fingerprints of the polymerases to show the special roles of polymerase delta on both strands during replication i...
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Nature Portfolio
2019
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oai:doaj.org-article:7b4b72b62f4042e1ae134de4b46a58662021-12-02T14:40:17ZRoles for DNA polymerase δ in initiating and terminating leading strand DNA replication10.1038/s41467-019-11995-z2041-1723https://doaj.org/article/7b4b72b62f4042e1ae134de4b46a58662019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11995-zhttps://doaj.org/toc/2041-1723DNA polymerases epsilon and delta, respectively, perform the majority of leading and lagging strand replication of the eukaryotic nuclear genome. Here the authors map the ribonucleotide fingerprints of the polymerases to show the special roles of polymerase delta on both strands during replication initiation and termination.Zhi-Xiong ZhouScott A. LujanAdam B. BurkholderMarta A. GarbaczThomas A. KunkelNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019) |
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Science Q Zhi-Xiong Zhou Scott A. Lujan Adam B. Burkholder Marta A. Garbacz Thomas A. Kunkel Roles for DNA polymerase δ in initiating and terminating leading strand DNA replication |
description |
DNA polymerases epsilon and delta, respectively, perform the majority of leading and lagging strand replication of the eukaryotic nuclear genome. Here the authors map the ribonucleotide fingerprints of the polymerases to show the special roles of polymerase delta on both strands during replication initiation and termination. |
format |
article |
author |
Zhi-Xiong Zhou Scott A. Lujan Adam B. Burkholder Marta A. Garbacz Thomas A. Kunkel |
author_facet |
Zhi-Xiong Zhou Scott A. Lujan Adam B. Burkholder Marta A. Garbacz Thomas A. Kunkel |
author_sort |
Zhi-Xiong Zhou |
title |
Roles for DNA polymerase δ in initiating and terminating leading strand DNA replication |
title_short |
Roles for DNA polymerase δ in initiating and terminating leading strand DNA replication |
title_full |
Roles for DNA polymerase δ in initiating and terminating leading strand DNA replication |
title_fullStr |
Roles for DNA polymerase δ in initiating and terminating leading strand DNA replication |
title_full_unstemmed |
Roles for DNA polymerase δ in initiating and terminating leading strand DNA replication |
title_sort |
roles for dna polymerase δ in initiating and terminating leading strand dna replication |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/7b4b72b62f4042e1ae134de4b46a5866 |
work_keys_str_mv |
AT zhixiongzhou rolesfordnapolymerasedininitiatingandterminatingleadingstranddnareplication AT scottalujan rolesfordnapolymerasedininitiatingandterminatingleadingstranddnareplication AT adambburkholder rolesfordnapolymerasedininitiatingandterminatingleadingstranddnareplication AT martaagarbacz rolesfordnapolymerasedininitiatingandterminatingleadingstranddnareplication AT thomasakunkel rolesfordnapolymerasedininitiatingandterminatingleadingstranddnareplication |
_version_ |
1718390364624125952 |