Prognostic Value of Biomarkers in Children and Adolescents With Orthostatic Intolerance

Orthostatic intolerance (OI) refers to a series of symptoms that occur during upright standing, which can be relieved when returned to the supine position. OI is a common cause of syncope in children and adolescents. In recent years, more and more studies have been carried out to assess the prognosi...

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Autores principales:	Huijuan Yan, Shuo Wang, Hong Cai, Juan Zhang, Ping Liu, Yuwen Wang, Runmei Zou, Cheng Wang
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	biomarkers prognosis children adolescents orthostatic intolerance Pediatrics RJ1-570
Acceso en línea:	https://doaj.org/article/7b4f634e54de4c0e814467b47068a60d
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spelling	oai:doaj.org-article:7b4f634e54de4c0e814467b47068a60d2021-11-30T12:42:24ZPrognostic Value of Biomarkers in Children and Adolescents With Orthostatic Intolerance2296-236010.3389/fped.2021.752123https://doaj.org/article/7b4f634e54de4c0e814467b47068a60d2021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fped.2021.752123/fullhttps://doaj.org/toc/2296-2360Orthostatic intolerance (OI) refers to a series of symptoms that occur during upright standing, which can be relieved when returned to the supine position. OI is a common cause of syncope in children and adolescents. In recent years, more and more studies have been carried out to assess the prognosis of OI by using biomarkers, among which, flow-mediated vasodilation, left ventricular ejection fraction and fractional shortening, hemodynamic change during head-up tilt test, detection of 24-h urinary sodium excretion, body mass index, midregional pro-adrenomedullin, and erythrocytic H2S producing rate are relatively stable, inexpensive, and easy to obtain. With the help of biomarkers, individualized treatment can be carried out to improve the long-term prognosis of children and adolescents with OI. This article reviews the prognostic value of biomarkers in children and adolescents with OI.Huijuan YanShuo WangHong CaiJuan ZhangPing LiuYuwen WangRunmei ZouCheng WangFrontiers Media S.A.articlebiomarkersprognosischildrenadolescentsorthostatic intolerancePediatricsRJ1-570ENFrontiers in Pediatrics, Vol 9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	biomarkers prognosis children adolescents orthostatic intolerance Pediatrics RJ1-570
spellingShingle	biomarkers prognosis children adolescents orthostatic intolerance Pediatrics RJ1-570 Huijuan Yan Shuo Wang Hong Cai Juan Zhang Ping Liu Yuwen Wang Runmei Zou Cheng Wang Prognostic Value of Biomarkers in Children and Adolescents With Orthostatic Intolerance
description	Orthostatic intolerance (OI) refers to a series of symptoms that occur during upright standing, which can be relieved when returned to the supine position. OI is a common cause of syncope in children and adolescents. In recent years, more and more studies have been carried out to assess the prognosis of OI by using biomarkers, among which, flow-mediated vasodilation, left ventricular ejection fraction and fractional shortening, hemodynamic change during head-up tilt test, detection of 24-h urinary sodium excretion, body mass index, midregional pro-adrenomedullin, and erythrocytic H2S producing rate are relatively stable, inexpensive, and easy to obtain. With the help of biomarkers, individualized treatment can be carried out to improve the long-term prognosis of children and adolescents with OI. This article reviews the prognostic value of biomarkers in children and adolescents with OI.
format	article
author	Huijuan Yan Shuo Wang Hong Cai Juan Zhang Ping Liu Yuwen Wang Runmei Zou Cheng Wang
author_facet	Huijuan Yan Shuo Wang Hong Cai Juan Zhang Ping Liu Yuwen Wang Runmei Zou Cheng Wang
author_sort	Huijuan Yan
title	Prognostic Value of Biomarkers in Children and Adolescents With Orthostatic Intolerance
title_short	Prognostic Value of Biomarkers in Children and Adolescents With Orthostatic Intolerance
title_full	Prognostic Value of Biomarkers in Children and Adolescents With Orthostatic Intolerance
title_fullStr	Prognostic Value of Biomarkers in Children and Adolescents With Orthostatic Intolerance
title_full_unstemmed	Prognostic Value of Biomarkers in Children and Adolescents With Orthostatic Intolerance
title_sort	prognostic value of biomarkers in children and adolescents with orthostatic intolerance
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/7b4f634e54de4c0e814467b47068a60d
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Prognostic Value of Biomarkers in Children and Adolescents With Orthostatic Intolerance

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