IMP-68, a Novel IMP-Type Metallo-β-Lactamase in Imipenem-Susceptible <named-content content-type="genus-species">Klebsiella pneumoniae</named-content>

IMP-68, a Novel IMP-Type Metallo-β-Lactamase in Imipenem-Susceptible <named-content content-type="genus-species">Klebsiella pneumoniae</named-content>

ABSTRACT We recently detected a novel variant of an IMP-type metallo-β-lactamase gene (blaIMP-68) from meropenem-resistant but imipenem-susceptible Klebsiella pneumoniae TA6363 isolated in Tokyo, Japan. blaIMP-68 encodes a Ser262Gly point mutant of IMP-11, and transformation experiments showed that...

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Auteurs principaux: Hiroaki Kubota, Yasunori Suzuki, Rumi Okuno, Yumi Uchitani, Tsukasa Ariyoshi, Nobuyuki Takemura, Fuminori Mihara, Kazuhisa Mezaki, Norio Ohmagari, Mari Matsui, Satowa Suzuki, Tsuyoshi Sekizuka, Makoto Kuroda, Keiko Yokoyama, Kenji Sadamasu
Format: article
Langue:EN
Publié: American Society for Microbiology 2019
Sujets:
Enterobacteriaceae
Klebsiella
antibiotic resistance
carbapenems
enzyme kinetics
genome analysis
Microbiology
QR1-502
Accès en ligne:https://doaj.org/article/7b63ec9a5fe34e238045334cf4961b0b
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https://doaj.org/article/7b63ec9a5fe34e238045334cf4961b0b

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