Design and synthesis of a new conjugate of a tris(3-hydroxy-4-pyridinone) chelator (KC18) for potential use as gallium-68-labeled prostate-specific membrane antigen (PSMA) radiopharmaceutical
Prostate-specific membrane antigen (PSMA) is considered a significant target for the diagnosis and therapy of prostate cancer. 2-[3-(1,3-dicarboxypropyl)-ureido]pentanedioic acid (DUPA) is a promising binding motif that has been proved to target PSMA successfully. 3-Hydroxy-4-pyridinone units contai...
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| Auteurs principaux: | , , , , |
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| Format: | article |
| Langue: | EN |
| Publié: |
Elsevier
2021
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| Sujets: | |
| Accès en ligne: | https://doaj.org/article/7b690681e2df43a3ae95e7c4bfe5b383 |
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