Targeting the mTOR pathway uncouples the efficacy and toxicity of PD-1 blockade in renal transplantation
The use of immune checkpoint inhibitors (ICI) in cancer patients with solid organ allografts is hampered due to potential organ rejection. Here, the authors present a case report of a patient with kidney allograft and show that treatment with the mTOR inhibitor sirolimus preserves peripheral toleran...
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Autores principales: | , , , , , , , , , , , |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
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Materias: | |
Acceso en línea: | https://doaj.org/article/7b6d74e8eca445f991f3a9a988480cef |
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