Mononucleotide repeat expansions with non-natural polymerase substrates

Abstract Replicative strand slippage is a biological phenomenon, ubiquitous among different organisms. However, slippage events are also relevant to non-natural replication models utilizing synthetic polymerase substrates. Strand slippage may notably affect the outcome of the primer extension reacti...

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Autores principales: Alexander V. Chudinov, Vadim A. Vasiliskov, Viktoriya E. Kuznetsova, Sergey A. Lapa, Natalia A. Kolganova, Edward N. Timofeev
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/7b73fccda1b24e75804200257fc598d1
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