Mononucleotide repeat expansions with non-natural polymerase substrates
Abstract Replicative strand slippage is a biological phenomenon, ubiquitous among different organisms. However, slippage events are also relevant to non-natural replication models utilizing synthetic polymerase substrates. Strand slippage may notably affect the outcome of the primer extension reacti...
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Autores principales: | Alexander V. Chudinov, Vadim A. Vasiliskov, Viktoriya E. Kuznetsova, Sergey A. Lapa, Natalia A. Kolganova, Edward N. Timofeev |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/7b73fccda1b24e75804200257fc598d1 |
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