Aging and Hypercholesterolemia Differentially Affect the Unfolded Protein Response in the Vasculature of <italic toggle="no">ApoE</italic><sup>−/−</sup> Mice

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Aging and Hypercholesterolemia Differentially Affect the Unfolded Protein Response in the Vasculature of <italic toggle="no">ApoE</italic><sup>−/−</sup> Mice

Background Persistent activation of endoplasmic reticulum stress and the unfolded protein response (UPR) induces vascular cell apoptosis, contributing to atherogenesis. Aging and hypercholesterolemia are 2 independent proatherogenic factors. How they affect vascular UPR signaling remains unclear. Me...

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Autores principales:	Yuxiang Zhou, Xueping Wan, Kerstin Seidel, Mo Zhang, Jena B. Goodman, Francesca Seta, Naomi Hamburg, Jingyan Han
Formato:	article
Lenguaje:	EN
Publicado:	Wiley 2021
Materias:	aging apoE deficient mice hypercholesterolemia unfolded protein response vascular cells Diseases of the circulatory (Cardiovascular) system RC666-701
Acceso en línea:	https://doaj.org/article/7b7730c287e648edad5d66189bb73eea
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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