Aging and Hypercholesterolemia Differentially Affect the Unfolded Protein Response in the Vasculature of <italic toggle="no">ApoE</italic><sup>−/−</sup> Mice
Background Persistent activation of endoplasmic reticulum stress and the unfolded protein response (UPR) induces vascular cell apoptosis, contributing to atherogenesis. Aging and hypercholesterolemia are 2 independent proatherogenic factors. How they affect vascular UPR signaling remains unclear. Me...
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Autores principales: | , , , , , , , |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Wiley
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/7b7730c287e648edad5d66189bb73eea |
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