The Zinc Finger Protein Mig1 Regulates Mitochondrial Function and Azole Drug Susceptibility in the Pathogenic Fungus <named-content content-type="genus-species">Cryptococcus neoformans</named-content>

The Zinc Finger Protein Mig1 Regulates Mitochondrial Function and Azole Drug Susceptibility in the Pathogenic Fungus <named-content content-type="genus-species">Cryptococcus neoformans</named-content>

ABSTRACT The opportunistic pathogen Cryptococcus neoformans causes fungal meningoencephalitis in immunocompromised individuals. In previous studies, we found that the Hap complex in this pathogen represses genes encoding mitochondrial respiratory functions and tricarboxylic acid (TCA) cycle componen...

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Autores principales: Mélissa Caza, Guanggan Hu, Michael Price, John R. Perfect, James W. Kronstad
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2016
Materias:
carbon metabolism
cell wall
macrophages
regulation
TOR kinase
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/7b787b0b040c4e8ca8d739877cdca17a
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