Interleukin-36β provides protection against HSV-1 infection, but does not modulate initiation of adaptive immune responses

Interleukin-36β provides protection against HSV-1 infection, but does not modulate initiation of adaptive immune responses

Abstract Interleukin-36 (IL-36) represents three cytokines, IL-36α, IL-36β and IL-36γ, which bind to the same receptor, IL-1RL2; however, their physiological function(s) remain poorly understood. Here, the role of IL-36 in immunity against HSV-1 was examined using the flank skin infection mouse mode...

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Autores principales: Katelynn A. Milora, Siva R. Uppalapati, Julio C. Sanmiguel, Wei Zou, Liselotte E. Jensen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/7b7a12157bfa4f488dd7a6d2de90cae1
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